Dear Wykie in South Africa:
In answer to your question re your wife's pain, from this article it would
appear that chronic pain is more common in people with PD than the general
population. I'm not sure if this is the article you missed that I posted,
but there are several articles on the internet re pain and PD if you search
using "chronic pain in Parkinson's disease". Also, I don't know if it is
more common in the US; this article suggests it is underreported. I am not
qualified to offer advice, I just post. There may be medical doctors on
this List who could help you. However, I think we would all wish you and
your wife well. I get these painful leg and foot spasms, but nothing like
what your wife suffers. Perhaps you will hear from others on the List with
similar symptoms.
Ray
Chronic pain in Parkinson's disease: the cross-sectional French DoPaMiP
survey.
Nègre-Pagès L, Regragui W, Bouhassira D, Grandjean H, Rascol O; DoPaMiP
Study Group.
Collaborators (58)
Attal N, Andrieu S, Bouhassira D, Chollet F, Demonet JF, Fourrier A, Gasquet
I, Grandjean H, Mestre ML, Lazorthes Y, Lepine JP, Montastruc JL, Nègre
Pagès L, Rascol O, Senard JM, Tiberge M, Angibaud G, Attané F, Azais F,
Vuillemin CA, Balagué JP, Barreda M, Benazet M, Bonenfant F, Boulesteix JM,
Carel C, Castan D, Chapelle M, Chopin MC, Cochen V, Colombier C, Damase L,
Danielli A, Darmanaden R, David J, Delage W, Faucheux JM, Aguié SF, Chaumeil
CG, Henry P, Jardillier B, Regragui W, Zermati JR, Rouane JR, Rougié MH,
Salandini AM, Senard A, Siboni J, Soulages X, Stambouli N, Aristin M,
Hurault C, Bonenfant S, De Llobet M, Guillaud E, Llau ME, Mabialah A, Milhet
A.
Department of Clinical Pharmacology, University Hospital, Toulouse, France.
Pain is a frequent, but poorly studied symptom of Parkinson's disease (PD).
DoPaMiP survey aimed to assess the prevalence of chronic pain in PD, to
describe PD patients with chronic pain, and to record analgesic consumption.
About 450 parkinsonian patients underwent structured standardized clinical
examination and completed self-reported questionnaires in a cross sectional
survey. Pains related or unrelated to PD were identified according to
predefined criteria. About 98 patients with other chronic disorders than PD
were examined to assess if pain was more frequent in PD than in this
population. Two thirds parkinsonian patients (278 of 450) had chronic pain.
Twenty-five patients with non-chronic pain (<3-month duration) were excluded
from subsequent analysis. Twenty six percent (111 of 425) parkinsonian
patients had pain unrelated to PD ("non-PD-pain", caused mainly by
osteoarthritis), while 39.3% (167 of 425) had chronic pain related to PD
("PD-pain"). In this last group, PD was the sole cause of pain in 103 and
indirectly aggravated pain of another origin (mainly osteoarthritis) in 64.
Parkinsonian patients with "PD-pain" were younger at PD onset, had more
motor complications, more severe depressive symptoms than those without pain
or with "non-PD pain." "PD-pain" was more intense (P = 0.03), but was less
frequently reported to doctors (P = 0.02), and was associated with less
frequent analgesic consumption than "non-PD-pain." Pain was twice more
frequent in PD patients than in patients without PD after adjustment for
osteo-articular comorbidities (OR = 1.9; 95% CI 1.2-3.2). Chronic pain is
frequent but underreported in PD. Awareness of this problem should be
increased and the assessment of analgesic strategies improved. Copyright
2008 Movement Disorder Society.
PMID: 18546344 [PubMed - in process]
Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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