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ExPASy will give you a picture of Parkinson's Disease Map O9 Biochemical Pathways Kegg hsa05020 will show a picture of the many Parkinson's Gene Mutations Sharon ----- Original Message ----- From: "rayilynlee" <[log in to unmask]> To: <[log in to unmask]> Sent: Friday, September 26, 2008 11:22 PM Subject: Inheriting PD > Thursday, September 25, 2008 > What are your chances of inheriting PD > If any member of your family has a history of PD, it is highly probable > that you might be predisposed to the disease. The gene which has created a > buzz in the scientific community for its role in PD is LRRK2. It is a > relatively new gene and lots of scientific research is being carried out > now and information is pouring in at a constant pace. > The mutation which has been prominent is the G2019S mutation on the LRRK2 > gene found in chromosome 12. The single-letter change in the DNA code > dramatically increases a person's odds of developing Parkinson's from one > or two in a hundred to as much as eight in 10. One recent study found that > a person who inherits the mutation has a 28% chance of developing > Parkinson's by the age of 59, 51% by the age of 69 and 74% by the age of > 79 (Healy et al. 2008, Lancet, 7, 583-590). > Posted by Saurabh Sen at 10:29 AM > > Rayilyn Brown > Director AZNPF > Arizona Chapter National Parkinson Foundation > [log in to unmask] > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn