Hi, 6. The Scientist news blog: Obama good for science, experts say This looks like spam to me. Let's wait and see what happens before we coronate him? Brian -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of PARKINSN automatic digest system Sent: Saturday, November 08, 2008 12:00 AM To: [log in to unmask] Subject: PARKINSN Digest - 6 Nov 2008 to 7 Nov 2008 (#2008-259) There are 6 messages totalling 306 lines in this issue. Topics of the day: 1. Question on 'Thrush' 2. A friend wants to Share their favorite sites with you 3. FierceBiotech: Mayo Clinic can't compete, axes clinical trial unit 4. Fw: CAMR Election Update - Stem Cells 5. Japanese researchers make brain tissues from stem cells 6. The Scientist news blog: Obama good for science, experts say ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- Date: Thu, 6 Nov 2008 11:07:29 -0800 From: Sue Horger <[log in to unmask]> Subject: Question on 'Thrush' I have been diagnosed with PD for about 5 years. My symptons are somewhat in check with small amounts of Sinemet, and lots of vitamins, minerals, herbs, etc. But I do have a bad case of Thrush - the coating of the tongue and mouth. I've been prescribed Nystatin which sometimes works a little but not for long. It comes back almost every morning. Does anyone have any history of thrush with PD, and what did you do/ are you doing about it? Is this a side effect of other medications, or is perhaps not connected to Parkinson's at all? Thanks for all the great discourse on this site! Sue, Southern California ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ------------------------------ Date: Thu, 6 Nov 2008 13:54:33 +0100 From: "schild.m" <[log in to unmask]> Subject: Re: A friend wants to Share their favorite sites with you > StumbleUpon do we need Spam on this list? maryse ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ------------------------------ Date: Thu, 6 Nov 2008 19:00:26 -0500 From: Carolyn Stephenson <[log in to unmask]> Subject: FierceBiotech: Mayo Clinic can't compete, axes clinical trial unit Mayo Clinic can't compete, axes clinical trial unit By John Carroll http://tinyurl.com/5gcb4j (copy/paste URL to read) Also see: Minneapolis/St Paul Business Journal: http://tinyurl.com/5kodbq The Mayo Clinic is getting out of the business of conducting clinical trials for drug developers, citing a low-cost environment that has made the world renowned organization uncompetitive. Fifty-seven of the 100 people working for the Mayo Clinical Trial Services unit will be affected in the near or short term, though Mayo said that it expects to move most of the personnel to other jobs in their organization. In the meantime, it's stopped taking new business and will wrap the trials underway. Most will be completed by the end of 2010. "Analysis of Mayo Clinical Trial Services showed that its business model for clinical trials is not competitive in a clinical-trials marketplace driven by low-cost, routine clinical trials," the Mayo Clinic said in a statement. "The assessment also concluded that the clinical trials unit would see substantial financial losses into the foreseeable future." ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ------------------------------ Date: Fri, 7 Nov 2008 04:49:40 GMT From: "[log in to unmask]" <[log in to unmask]> Subject: Fw: CAMR Election Update - Stem Cells <?xml:namespace prefix =3D o ns =3D "urn:schemas-microsoft-com:office:of= fice" />FWD from Coalition for the Advancement of Medical Research: = The results of yesterday=92s election bode well for the future of stem c= ell research in our nation. = At the national level, CAMR will move forward with our plan to work wit= h President-elect Obama and his administration to quickly remove Preside= nt Bush=92s limitations on embryonic stem cell research. As we spelled = out in our testimony to the Democratic Platform Committee, we believe th= at President Obama should issue an immediate Executive Order that would = result in a reversal of the current policy. We are reaching out to Pres= ident-elect Obama=92s transition team now and will keep you informed of = our progress. = While the national election has the attention of entire world, two impor= tant state ballots were determined yesterday that also have an extraordi= nary impact on the future of stem cell research. The <?xml:namespace prefix =3D st1 ns =3D "urn:schemas-microsoft-com:of= fice:smarttags" />Michigan ballot, =93Proposition 2,=94 was successfully= passed by a defendable margin in the state. As you know, CAMR strongl= y supported this ballot question that will lift Michigan=92s strict rest= rictions on embryonic stem cell research. The ballot initiative we strongly opposed in Colorado, =93Proposition 4= 8,=94 was soundly defeated. This proposed amendment to the Colorado con= stitution would have redefined a person as a fertilized egg and would ha= ve profoundly limited research. Over 70% of Colorado=92s citizens voted= against the measure. = We have been in this long fight together, and we are now closer than eve= r to our goal of moving embryonic stem cell research forward in our nati= on. We have remained strong because we share the belief that we can end= the suffering of over 100 million patients suffering from diseases and = conditions that can benefit from embryonic stem cell research. = There are two things you can do today to help: Send a Letter to the Editor You can customize the letter below and send it to your hometown newspape= r. Please try to personalize it as best you can -- perhaps adding a ref= erence to something you or a family member may be living with or struggl= ing with. = To find out where to send it, please refer to your hometown newspaper's= web site (the Contact Us section or Opinion page usually lists an email= address to send LTEs), and include your full name, city and state, emai= l address, and a phone number where you can be reached for verification.= Remember not to go over 150 words. Most newspapers won't accept or ev= en review letters that are longer that that. Please let us know if your= letter runs in your newspaper -- we'd love to see it! = LETTER TO THE EDITOR TEXT: = Dear Editor: = A new President brings hope on many fronts. For me, I am most hopeful a= bout positive, forward-thinking change in our nation's stem cell researc= h policy. As someone who, [PERSONALIZATION MENTION HERE], I call on P= resident-elect Obama to take his support for embryonic stem cell resear= ch from the Senate to the White House and enact ethical and responsible = federal policy around embryonic stem cell research so our nation's scien= tists can do their best work. Embryonic stem cell research has shown gr= eat hope these past ten years. It deserves the chance to show its real = power in finding better treatments and cures. = Sincerely, = NAME CITY, STATE PHONE EMAIL = Sign the International Society for Stem Cell Research Letter = The International Society for Stem Cell Research (ISSCR), a CAMR member,= has drafted an open letter to reiterate the urgent need for support for= all types of stem cell research. CAMR will be signing on, and we are e= ncouraging CAMR member organizations, scientists, practitioners, medica= l professionals and others in related fields to add their signatures as = well. If you would like to do so, please click here: = http://www.isscr.org/ScienceStatementEndorsement.cfm = We invite you to join us in spreading the word about this important open= letter. For more information, please click here: = = http://www.isscr.org/ScienceStatementEndorsers.cfm = Thank you for everything you do. Be sure to visit our website at www.ca= mradvocacy.org for more information and breaking news. = Sincerely, = = Amy Comstock Rick CAMR President www.camradvocacy.org = ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ------------------------------ Date: Fri, 7 Nov 2008 04:44:17 GMT From: "[log in to unmask]" <[log in to unmask]> Subject: Japanese researchers make brain tissues from stem cells Yahoo News Japanese researchers make brain tissues from stem cellsThu Nov 6, 3:36 a= m ET TOKYO (AFP) =96 Japanese researchers said Thursday they had created= functioning human brain tissues from stem cells, a world first that has= raised new hopes for the treatment of disease. Stem cells taken from human embryos have been used to form tissues of th= e cerebral cortex, the supreme control tower of the brain, according to = researchers at the government-backed research institute Riken. The tissues self-organised into four distinct zones very similar to the = structure seen in human foetuses, and conducted neuro-activity such as t= ransmitting electrical signals, the institute said. Research on stem cells is seen as having the potential to save lives by = helping to find cures for diseases such as cancer and diabetes or to rep= lace damaged cells, tissues and organs. The team's previous studies showed stem cells differentiated into distin= ct cells but until now they had never organised into functioning tissues= . "In regenerative therapy, only a limited number of diseases can be cured= with simple cell transplants. Transplanting tissues could raise hopes f= or greater functional recovery," the institute said in a statement. "Cultivated tissues are still insufficient and too small to be used to t= reat stroke patients. But study of in-vitro cultivation of more mature c= ortex tissues, such as those with six zones like in the adult human brai= n, will be stepped up," it said. The tissues could also serve as "a mini organ" for use in studying the c= ause of the Alzheimer's disease and developing vaccines, it said. Embryonic stem cells are harvested by destroying a viable embryo, a proc= ess that some people find unacceptable. Riken said cortex tissues were also obtained from "induced pluripotent s= tem cells," which are similar to embryonic stem cells but artificially i= nduced, typically from adult cells such as skin cells. The research was led by Yoshiki Sasai at Riken Centre for Development Bi= ology in western Japan's Kobe. The cultivated tissues look like minature mushrooms two millimetres (0.0= 8 inches) in diametre. The team also succeeded in making cortex tissues from the embryonic stem= cells of mice. Using mouse tissues, scientists confirmed they had formed a network of n= eurons that properly respond to stimulus. The tissues can also be selectively induced to different cortex types co= ntrolling memories, visual sensation and other tasks. The findings of the study were published in the November 6 online journa= l Cell Stem Cell in the United States. http://news.yahoo.com/s/afp/20081106/ts_afp/healthsciencestemcelljapan www.pdpipeline.org ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ------------------------------ Date: Thu, 6 Nov 2008 18:53:53 -0500 From: Carolyn Stephenson <[log in to unmask]> Subject: The Scientist news blog: Obama good for science, experts say Obama good for science, experts say Posted by Bob Grant [Entry posted at 5th November 2008 05:06 PM GMT] May require FREE registration: http://www.the-scientist.com/blog/display/55167/ Science groups are welcoming Senator Barack Obama's landslide victory as the 44th President of the United States. Throughout his campaign, Obama made several promises regarding American science, including doubling the budgets of key research agencies, such as the National Institutes of Health (NIH), the National Science Foundation (NSF), and the Department of Energy's Office of Science, over a decade. "We're looking forward to working with Obama as well as the Congress to make these promises come true," Richard Marchase, president of the Federation of American Societies for Experimental Biology (FASEB), told The Scientist. But what actions must Obama undertake to buoy US science? 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