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from Viartis:  28th January 2009 - New research
PARKINSON'S DISEASE IN TWINS
Neurobiology of Aging [2008] 29 (12) : 1765-1773 (Wirdefeldt K, Gatz M, 
Bakaysa SL, Fiske A, Flensburg M, Petzinger GM, Widner H, Lew MF, Welsh M, 
Pedersen NL.)  Complete abstract
It is claimed by some people that Parkinson's Disease is genetic - not 
merely that genetic mutations can lead to Parkinson's Disease in some 
people, which does occur, but that Parkinson's Disease occurs far more 
commonly when somebody has a close relative who has Parkinson's Disease. 
Genetically, twins are the closest of all relatives. This study assessed how 
commonly Parkinson's Disease occurred in both twins. Nearly 50,000 twins 
were assessed. Out of those, 132 people were found to have Parkinson's 
Disease. Over 7% of cases reported a first degree relative with Parkinson's 
Disease. However, only three of those people with Parkinson's Disease were 
found to be pairs of twins. This made the likelihood of both twins 
developing Parkinson's Disease very small. It completely contradicts the 
notion that Parkinson's Disease occurs far more commonly amongst close 
relatives. Besides relatives passing on their genes, they often pass on 
aspects of their lifestyle. Lifestyle similarities rather than genetics 
would better explain more than one person within the same family having 
Parkinson's Disease.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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