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THE WORLD'S HIGHEST PREVALENCE OF PARKINSON'S DISEASE
Neuroepidemiology [2009] 32 (4) : 263-269 (Yamawaki M, Kusumi M, Kowa H, 
Nakashima K.) Complete abstract
Japan might now be the country with the world's highest prevalence of 
Parkinson's Disease. The U.S.A. was the country with the highest known 
prevalence rates for Parkinson's Disease. However, such high prevalence 
rates were only found in Nebraska, U.S.A., where the heavy pesticide use in 
what is a largely agricultural area may have increased prevalence rates 
beyond the norm. Other isolated areas have very high prevalence rates, such 
as in the vicinity of ferromanganese plants in Brescia, Italy, and amongst 
the Parsi in Bombay, whose rituals cause them to inhale fumes of the 
potentially toxic Aspand seeds. For more information go to Prevalence of 
Parkinson's Disease. The prevalence of Parkinson's Disease in Japan has not 
previously been high. However, this study shows that the prevalence in Japan 
has increased continuously up to a recent high of 192 per 100,000 people. 
Part of the increase would be due to the greater life expectancy. A second 
factor might actually be the time that has elapsed since the Second World 
War. There was a high death rate during the Second World War of men who 
would have subsequently been at the age most likely to have Parkinson's 
Disease. This is probably why Japan is the only country in the world that 
had far more women than men with Parkinson's Disease. Over time this factor 
is reducing in significance because most men of the age most likely to have 
Parkinson's Disease are now too young to have died during the Second World 
War.

10th February 2009 - New research
Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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