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16th February 2009 - News report
SUPER MICROSCOPE TO DETECT PARKINSON'S DISEASE
Researchers from Keele University, in England, are using a 
"super-microscope" to diagnose Parkinson's Disease. They have been using a 
synchotron, or Diamond Light Source. The synchotron  is a large 
doughnut-shaped particle accelerator, the size of five football pitches. It 
fires particles at near the speed of light, focusing them into a beam less 
than a single cell in diameter. It allows researchers to observe metal ions, 
particularly iron levels, in individual brain cells that are affected by 
Parkinson's Disease. For more information go to the news article. Iron is 
essential for the formation of L-dopa. The Birkmayer studies showed that 
iron caused a decrease in Parkinson's Disease in all of the more than one 
hundred people they tested. However, when L-dopa is deficient, as occurs in 
Parkinson's Disease, iron can sometimes accumulate in an attempt to increase 
L-dopa formation. So instead of iron accumulation causing Parkinson's 
Disease, which is what the method of diagnosis is wrongly based on, 
Parkinson's Disease can sometimes cause an iron accumulation. Many people 
with Parkinson's Disease do not have any accumulation of iron. So the method 
does not appear to have any likelihood of being as effective as existing 
scanning methods.

13th February 2009 - New research from Viartis

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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