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Hey! I am an Ashkenazi Jew... I'd like a word or two with that ancestor who apparently bequeathed this unwelcome heritage. This should spur even more intensive research on thepart of the Israelis, who are already deeply into PD research... Thanks, Ray On 16-Mar-09, at 7:31 PM, rayilynlee wrote: > PARKINSON'S DISEASE NEWS > from Viartis > > 16th March 2009 - New research > 2000 YEAR OLD CASE OF PARKINSON'S DISEASE > > Neurogenetics [2009] Mar 13. [Epub ahead of print] (Bar-Shira A, > Hutter CM, Giladi N, Zabetian CP, Orr-Urtreger A.) Complete abstract > > It is often claimed that Parkinson's Disease was discovered in 1817 > by James Parkinson. However, there have been descriptions and > treatments of Parkinson's Disease since ancient times. For more > information go to the History of Parkinson's Disease. There is a > genetic mutation called LRRK2 G2019S that increases the likelihood > of Parkinson's Disease. It is most common amongst Ashkenazi Jews. > Ashkenazi Jews descend from Jews in medieval Germany. It was found > that Ashkenazi Jews who had Parkinson's Disease due to this genetic > mutation had a common ancestor who lived nearly 2000 years ago. > Their ancestor, who would have probably had Parkinson's Disease, > lived approximately 1,830 (1,560-2,160) years ago, around the second > century A.D., after the second Jewish Diaspora. At that time, Israel > was still under Roman rule. Genetic disorders are usually acquired > by one person at some point, and are then inherited by their > descendents for ever more. So some people have Parkinson's Disease > because of somebody who lived over a thousand years ago. For more > information go to Genetic causes of Parkinson's Disease. > > Rayilyn Brown > Director AZNPF > Arizona Chapter National Parkinson Foundation > [log in to unmask] > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn