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PARKINSON'S DISEASE NEWS from Viartis 16th March 2009 - New research 2000 YEAR OLD CASE OF PARKINSON'S DISEASE Neurogenetics [2009] Mar 13. [Epub ahead of print] (Bar-Shira A, Hutter CM, Giladi N, Zabetian CP, Orr-Urtreger A.) Complete abstract It is often claimed that Parkinson's Disease was discovered in 1817 by James Parkinson. However, there have been descriptions and treatments of Parkinson's Disease since ancient times. For more information go to the History of Parkinson's Disease. There is a genetic mutation called LRRK2 G2019S that increases the likelihood of Parkinson's Disease. It is most common amongst Ashkenazi Jews. Ashkenazi Jews descend from Jews in medieval Germany. It was found that Ashkenazi Jews who had Parkinson's Disease due to this genetic mutation had a common ancestor who lived nearly 2000 years ago. Their ancestor, who would have probably had Parkinson's Disease, lived approximately 1,830 (1,560-2,160) years ago, around the second century A.D., after the second Jewish Diaspora. At that time, Israel was still under Roman rule. Genetic disorders are usually acquired by one person at some point, and are then inherited by their descendents for ever more. So some people have Parkinson's Disease because of somebody who lived over a thousand years ago. For more information go to Genetic causes of Parkinson's Disease. Rayilyn Brown Director AZNPF Arizona Chapter National Parkinson Foundation [log in to unmask] ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn