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Hi, The approach I've been using (so far without success) is to do some genealogy work looking for photographs etc (I think I could recognize untreated advanced pd). I also called and talked to my older relatives and asked if they might recall anyone with shuffling gait, stooped shoulders, bad posture, unintelligible speech. My mom said sure but they were all drunks. \Randy Games to Entertain Your Brain http://www.stargraphics.com/ ----- Original Message ----- From: "JOHN YOCHIM" <[log in to unmask]> To: <[log in to unmask]> Sent: Saturday, March 21, 2009 2:20 PM Subject: Re: 2000 yr old case of PD > My Grandfather on my mothers side had PD. My whole family decends from > German ancestry but we have no record of members having Pd except for the > Grandfather. I wonder if there is a way to trace back to uncover past > generations in the family? Not that it wll help me at this time. I am > hoping that my children do not acquire the problem. > The spinal cord info looks promising. Thanks for all the updates. > John > > --- On Fri, 3/20/09, rayilynlee <[log in to unmask]> wrote: > From: rayilynlee <[log in to unmask]> > Subject: Re: 2000 yr old case of PD > To: [log in to unmask] > Date: Friday, March 20, 2009, 4:07 PM > > Murray and Steve > > I blame my grandfather for my PD. He was a disagreeable guy so it helps > to > have someone to blame, I think. > > However, nobody deserves this disease. > > Ray > > Rayilyn Brown > Director AZNPF > Arizona Chapter National Parkinson Foundation > [log in to unmask] > > -------------------------------------------------- > From: "Steve Rack" <[log in to unmask]> > Sent: Tuesday, March 17, 2009 2:18 PM > To: <[log in to unmask]> > Subject: Re: 2000 yr old case of PD > >>> PARKINSON'S DISEASE NEWS >>> from Viartis >>> >>> 16th March 2009 - New research >>> 2000 YEAR OLD CASE OF PARKINSON'S DISEASE >>> >>> Neurogenetics [2009] Mar 13. [Epub ahead of print] (Bar-Shira A, > Hutter CM, Giladi N, Zabetian CP, Orr-Urtreger A.) Complete abstract >>> >>> It is often claimed that Parkinson's Disease was discovered in > 1817 by James Parkinson. However, there have been descriptions and > treatments of > Parkinson's Disease since ancient times. For more information go to the > History of Parkinson's Disease. There is a genetic mutation called LRRK2 > G2019S that increases the likelihood of Parkinson's Disease. It is most > common amongst Ashkenazi Jews. Ashkenazi Jews descend from Jews in > medieval > Germany. It was found that Ashkenazi Jews who had Parkinson's Disease due > to > this genetic mutation had a common ancestor who lived nearly 2000 years > ago. > Their ancestor, who would have probably had Parkinson's Disease, lived > approximately 1,830 (1,560-2,160) years ago, around the second century > A.D., > after the second Jewish Diaspora. >> >> Thanks Ray. >> Now I have someone to point a finger at. My mom's father emigrated > from Hamburg. He died young so we will never know if he had Pd. Now, for > what > it's worth, we can blame Grandpa for Mom's and my Pd. >> I just reread this and it seems I've let some bitterness out. Maybe > I'd rather I didn't know about this. Another learning experience I > suppose. >> -- Steve in VT >> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: > mailto:[log in to unmask] >> In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn