John I would recommend Amantadine as it gives me a little boost. Helps you out in the afternoon rum dums. I have been taking it 2 years. I was diagnosed 16 years ago. I take sinemet, comtan, and amantadine. I don't feel dbs was the way to go for me. dbs in my opinion, is not necessary for me because my tremors are controlled with medications. Alan -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of rayilynlee Sent: Thursday, April 30, 2009 11:41 PM To: [log in to unmask] Subject: Re: Question re Amantadine use John I am sending your question to the List because I think there are quite a few folks who have used Amantadine. I never have, so I don't know much about it. I'm thinking you just won't know until you try it - at least that has been my experience with Sinemet - it helped on the first dose but never again even though I tried it again twice after taking it for a year several years ago. Mirapex and Requip, Comtan and Stalevo didn't help either, but DBS stopped my tremors. I read somewhere that DBS was the only thing that would help tremor. Good luck, Ray Rayilyn Brown Director AZNPF Arizona Chapter National Parkinson Foundation [log in to unmask] From: JOHN YOCHIM Sent: Thursday, April 30, 2009 7:38 PM To: rayilynlee Subject: Question re Amantadine use Ray, I am wondering if you or the folks on the listserve have experience using Amantadine 100mg medicine. My VA provider is recommending that in addition to Sinemet, that I take two Amamtadine tablets per day. This is supposed to assist the Sinemet in controlling my PD symptoms including tremor. There are side effects of course, which I am aware of. So, I would like to find out how well it is tolerated and if it has helped others. I was diagnosed in 05 with PD but the sinemet has not worked well or me in helping with the symptoms. I continue to take sinemet as it seems to help with anxiety. Thanks for your help in the past and hopefully you can shed some light on my question. Regards, John Y. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn