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 source:  Viartis

3rd May 2009 - New research
PRAMIPEXOLE CLINICAL TRIAL RESULTS

Pramipexole (known under the trade names Mirapexin®, Sifrol®, Mirapex® and 
Pexola®) is a drug that is used for Parkinson's Disease, on its own or with 
L-dopa. However, there are numerous possible side effects.  It is claimed 
that the outcome of a new study on Pramipexole is set to change the 
treatment of depressive symptoms in Parkinson's Disease because Pramipexole 
is claimed to relieve the depressive symptoms of Parkinson's Disease. 
However, the results show that the effect of Pramipexole was little better 
than the effect of a placebo : depression (reduced by -5.9 v -4.0), 
geriatric depression (improved by 2.5 v 1.7), Parkinson's Disease symptoms 
(reduced by -4.4 v -2), daily living (improved by -2.4 v -1.2). Those taking 
only a placebo improved on all the scales as well, thereby greatly reducing 
the actual benefit of Pramipexole. The placebo achieved a similar without 
the widespread side effects of Pramipexole.  For more information go to the 
News release. Previous research by the same author also showed that 
Pramipexole was not not much more effective for Parkinson's Disease 
depression than a placebo. For more information go to the  Complete 
abstract. In order to refer to this article on its own click here.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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