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----- Original Message ----- From: "Ernesto Divo" <[log in to unmask]> Subject: Re: Question re milk thistle and tyrosine > Have you heard of 'Dymatize Elite Whey Protein?' It contains L-tyrosine, a > long list of amino acids and a whole bunch of other goodies -------------------------------------------------------------------------------------------------- I am not a doctor of medicine; the following is not medical advice, only the personal opinion of the writer. Any contemplated change in treatment or medication must be referred to your treating medical practitioner. Dr James F. Slattery PhD Soc Sc ------------------------------------------------------------------------------------------------- Hi Ernesto, I am very wary of protein supplements taken at the same time as dopamine replacement therapies. The reason is, that animal protein (eggs, milk, butter, meat, fish, cream, cheese, etc), interferes with the adsorption of the active ingredient, L-DOPA (trade name Levodopa(R), a dopamine precursor converted in the body to dopamine). The levodopa in Sinemet(R), Parcopa(R), and Atamet(R) is carried to the brain by carbidopa. In Madopar(R) and Co-Beneldopa(R) the carrier is benzerazide. Both carriers inhibit aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC) , an enzyme that is important in the biosynthesis of L-DOPA to Dopamine (DA), and both do not pass the blood/brain barrier. Used in tandem with L-DOPA they increase the plasma half-life of levodopa from 50 minutes to 1 1/2 hours. They cannot cross the blood brain barrier. They thus prevent the conversion of L-DOPA to dopamine peripherally. This reduces the side effects caused by dopamine on the periphery, as well as increasing the concentration of L-DOPA and dopamine in the brain. They are absorbed from the small intestine, and carried in the blood to the blood/brain barrier, where the levodopa crosses over. In order to "trick" the body into doing this, the package was made to resemble a Large Molecule Amino Acid (LMAA), which, of course, animal protein is. The only problem is, that if the real LMAAs reach the absorption site in sufficient quantity, and at the appropriate time, some or all of the medication will not be absorbed within its half-life, thus negating that dose. To avoid this, the medication is best taken on an empty stomach, ie,one hour before meals, or two hours after. If this results in stomach aggravation, try a small meal of say, crackers and juice, which contain no animal protein, with or just before medication. Dr. J. F. Slattery PhD ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn