Have you heard of 'Dymatize Elite Whey Protein?' It contains L-tyrosine, a long list of amino acids and a whole bunch of other goodies... I buy mine at http://www.bodybuilding.com/store/dym/elite.html . I'm not advertising these guys, Google the store and the product. Ernesto On Thu, May 14, 2009 at 10:58 AM, <[log in to unmask]> wrote: > Oh boy, Ray. Wouldn't that be a great side effect. Let me know and maybe > I'll try it. > > Roberta Innarella > > > In a message dated 5/13/2009 2:00:52 A.M. Eastern Daylight Time, > [log in to unmask] writes: > > Roberta > > I don't take any MAO inhibitors or much else so the tyrosine is most > likely > OK for me. thanks for clarifying the issue. It would be great if I could > lose some fat. > Ray > Rayilyn Brown > Director AZNPF > Arizona Chapter National Parkinson Foundation > [log in to unmask] > > -------------------------------------------------- > From: <[log in to unmask]> > Sent: Sunday, May 10, 2009 8:23 AM > To: <[log in to unmask]> > Subject: Re: Question re milk thistleand tyrosine > > > > > > > The following taken from "Prescription for Nutritional Healing" Third > > Edition: > > > > "Tyrosine is important to overall metabolism. It is a precursor of > > adrenaline and the neurotransmiters norepinephrine and dopamine, which > > regulate > > mood and stimulate metabolism and the nervous system. Tyrosine acts as > a > > mood elevator; a lack of adequate amounts of tyrosine leads to a > > deficiency > > of norepinephrine in the brain, which in turn can result in depression. > > > It > > also acts as a mild antioxidant, suppresses the appetite, and helps to > > reduce body fat. It aids in the production of melanin (the pigment > > responsible > > for skin and hair color) and in the functions of the adrenal, thyroid, > > and > > pituitary glands. It is also involved in the metabolism of the amino > > acid > > phenylalanine. > > > > Tyrosine attaches to iodine atoms to form active thyroid hormones. > Not > > surprisingly, therefore, low plasma levels of tyrosine have been > > associated > > with hypothyroidism. Symptoms of tyrosine deficiency can also include > > low > > blood pressure, low body temperature (such as cold hands and feet), > and > > restless leg syndrome. > > > > Supplemental L-tyrosine has been used for stress reduction, and > research > > suggests it may be helpful against chronic fatigue and narcolepsy. It > > has > > been used to help individuals suffering from anxiety, depression, low > sex > > drive, allergies, and headaches, as well as persons undergoing > withdrawal > > from drugs. It may also help people with Parkinson's disease. > > > > Natural resources of tyrosine include almonds, avocados, bananas, dairy > > products, lima beans, pumpkin seeds, and sesame seeds. Tyrosine can > also > > be > > produced from phenylalanine in the body. Supplements of L-tyrosine > > should > > be taken at bedtime or with a high-carbohydrate meal so that it does > not > > have to complete for absorption with other amino acids. > > > > Persons taking monoamine oxidase (MAO)) inhibitors, commonly prescribed > > for depression, must strictly limit their intake of foods containing > > tyrosine > > and should not take any supplements containing L-tyrosine, as it may > lead > > to a sudden and dangerous rise in blood pressure. Anyone who takes > > prescription medication for depression should discuss necessary dietary > > restrictions with his or her physician." > > > > I take Azilect which is an MOA (B) not (A) inhibitor so I don't know if > > the last paragraph would apply as I obviously don't take it for > > depression > > but for PD. I guess I'll need to research further unless anyone on > this > > forum knows the answer. > > > > Roberta Innarella > > > > > > In a message dated 5/10/2009 3:27:33 A.M. Eastern Daylight Time, > > [log in to unmask] writes: > > > > Schaff: > > > > I ordered 1000 msg milk thistle and 500 msg L-tyrosine - is that the > > correct > > amount or not? > > thanks so much and for clarifying the bp issue. I couldn't find > > anything > > > > on line that said tyrosine caused high bp - and yes it did claim these > 2 > > supplements as treatment for PD. thanks so very much > > > > here's hoping....I don't take PD meds you know, but am getting worse > > > > Ray > > > > Rayilyn Brown > > Director AZNPF > > Arizona Chapter National Parkinson Foundation > > [log in to unmask] > > > > -------------------------------------------------- > > From: "Schaaf Angus / Meadow Creek Ranch" <[log in to unmask]> > > Sent: Sunday, May 10, 2009 8:09 PM > > To: <[log in to unmask]> > > Subject: Re: Question re milk thistleand tyrosine > > > >> To the best of my knowledge tyrosine has no impact on blood pressure. > It > >> is > >> a precursor necessary for the production of dopamine by the liver. It > is > >> quite beneficial. Salt and sugar as well as poor diets have more > impact > > on > >> BP . > >> Hope this helps. > >> If it werent for tyrosine in my program I couldnt do the 5 to 6 hours > of > >> walking I've been doing the last few days fixing storm damage on the > > ranch > >> fences. Needless to say by sundown I'm really wornout for the day. > >> Have a good Sunday Ray. > >> > >> ----- Original Message ----- > >> From: "rayilynlee" <[log in to unmask]> > >> To: <[log in to unmask]> > >> Sent: Friday, May 08, 2009 10:48 AM > >> Subject: Re: Question re milk thistle > >> > >> > >>> thanks Roberta - I take bp medication > >>> Ray > >>> > >>> Rayilyn Brown > >>> Director AZNPF > >>> Arizona Chapter National Parkinson Foundation > >>> [log in to unmask] > >>> > >>> -------------------------------------------------- > >>> From: <[log in to unmask]> > >>> Sent: Thursday, May 07, 2009 4:03 AM > >>> To: <[log in to unmask]> > >>> Subject: Re: Question re milk thistle > >>> > >>> > > >>> > > >>> > Doesn't Tyrosine increase blood pressure? > >>> > > >>> > Roberta Innarella > >>> > > >>> > > >>> > In a message dated 5/7/2009 2:01:57 A.M. Eastern Daylight Time, > >>> > [log in to unmask] writes: > >>> > > >>> > Yep! > >>> > > >>> > ----- Original Message ----- > >>> > From: "rayilynlee" <[log in to unmask]> > >>> > To: <[log in to unmask]> > >>> > Sent: Tuesday, May 05, 2009 9:45 AM > >>> > Subject: Re: Question re milk thistle > >>> > > >>> > > >>> >> gee, I didn't know milk thistle would help my liver produce > > dopamine. > >>> >> I > >>> >> started taking it for constipation. Do I need to take tyrosine > >>> >> with > >> it? > >>> >> > >>> >> Ray > >>> >> > >>> >> Rayilyn Brown > >>> >> Director AZNPF > >>> >> Arizona Chapter National Parkinson Foundation > >>> >> [log in to unmask] > >>> >> > >>> >> -------------------------------------------------- > >>> >> From: "Schaaf Angus / Meadow Creek Ranch" <[log in to unmask]> > >>> >> Sent: Tuesday, May 05, 2009 8:40 AM > >>> >> To: <[log in to unmask]> > >>> >> Subject: Question re Amantadine/ GSH importance > >>> >> > >>> >> > Couple of thoughts. > >>> >> > Have you tried to let your liver produce your dopamine needs > by > >> taking > >>> >> > tyrosine and milk thistle? > >>> >> > The natural production of GSH by the body is a little more > >>> > complicated > >>> >> > but > >>> >> > following is article from my archives that helps explain. > >>> >> > WHY GSH > >>> >> > Oxidative stress appears to play an important role in > >>> >> > degeneration > >> of > >>> >> > dopaminergic neurons of the substantia nigra (SN) associated > >>> >> with > >>> >> > Parkinson's disease (PD). The SN of early PD patients have > >>> >> > dramatically > >>> >> > decreased levels of the thiol tripeptide glutathione (GSH). GSH > >> plays > >>> >> > multiple roles in the nervous system both as an antioxidant > and > >>> a > >>> >> > redox > >>> >> > modulator. We have generated dopaminergic PC12 cell lines in > > which > >>> > levels > >>> >> > of > >>> >> > GSH can be inducibly down-regulated via doxycycline induction > of > >>> > antisense > >>> >> > messages against both the heavy and light subunits of > >>> >> > gamma-glutamyl-cysteine synthetase, the rate-limiting enzyme > in > >>> >> > glutathione > >>> >> > synthesis. Down-regulation of glutamyl-cysteine synthetase > >>> >> > results > >> in > >>> >> > reduction in mitochondrial GSH levels, increased oxidative > > stress, > >> and > >>> >> > decreased mitochondrial function. Interestingly, decreases in > >>> >> > mitochondrial > >>> >> > activities in GSH-depleted PC12 cells appears to be because of > a > >>> > selective > >>> >> > inhibition of complex I activity as a result of thiol > oxidation. > >> These > >>> >> > results suggest that the early observed GSH losses in the SN > may > >>> >> > be > >>> >> > directly > >>> >> > responsible for the noted decreases in complex I activity and > the > >>> >> > subsequent > >>> >> > mitochondrial dysfunction, which ultimately leads to > dopaminergic > >>> >> cell > >>> >> > death > >>> >> > associated with PD. > >>> >> > > >>> >> > WHY GLUTAMINE > >>> >> > Glutamine is an important mitochondrial substrate implicated in > > the > >>> >> > protection of cells from oxidant injury. Human pulmonary > >>> > epithelial-like > >>> >> > (A549) cells were exposed to 95% O(2) for 4 days in the > absence > > and > >>> >> > presence > >>> >> > of glutamine. Cell proliferation in normoxia was dependent on > >>> > glutamine, > >>> >> > and > >>> >> > glutamine deprivation markedly accelerated cell death in > > hyperoxia. > >>> >> > Glutamine significantly increased cellular ATP levels in > normoxia > >> and > >>> >> > prevented the loss of ATP in hyperoxia seen in > glutamine-deprived > >>> > cells. > >>> >> > Mitochondrial membrane potential as assessed by flow cytometry > > with > >>> >> > chloromethyltetramethylrosamine was increased by glutamine in > >>> >> > hyperoxia-exposed A549 cells, and a glutamine dose-dependent > >> increase > >>> > in > >>> >> > mitochondrial membrane potential was detected. > >> Glutamine-supplemented, > >>> >> > hyperoxia-exposed cells had a HIGHER O(2) consumption rate > and > > GSH > >>> >> > content. > >>> >> > Electron and fluorescence microscopy revealed that, in > > hyperoxia, > >>> >> > glutamine > >>> >> > protected cellular structures, especially mitochondria, from > >>> >> > damage. > >>> >> > In > >>> >> > hyperoxia, activity of the tricarboxylic acid cycle enzyme > >>> >> > alpha-ketoglutarate dehydrogenase was partially protected by > >>> >> > its > >>> > indirect > >>> >> > substrate, glutamine, indicating a mechanism of mitochondrial > >>> > protection. > >>> >> > THEREFORE: I take L-Glutamine and DHEA to increase the level > of > >>> >> > GSH > >>> >> > in > >>> >> > the > >>> >> > body naturally to further thwart the symptoms and destruction > of > >> P.D. > >>> >> > along > >>> >> > with my other vitamin/mineral protocol which exclude PD drugs. > As > > a > >>> > note. > >>> >> > I > >>> >> > never tried the Amantadine. My doctors forced me early to look > >>> > elsewhere > >>> >> > for > >>> >> > help since they couldnt due to lack of knowledge or incentive. > > Not > >>> >> > sure > >>> >> > which but I'm alot healthier for switching to a no drug > > protocol. > >>> >> > > >>> >> > ----- Original Message ----- > >>> >> > From: "Ernesto Divo" <[log in to unmask]> > >>> >> > To: <[log in to unmask]> > >>> >> > Sent: Sunday, May 03, 2009 12:24 PM > >>> >> > Subject: Re: Question re Amantadine use > >>> >> > > >>> >> > > >>> >> >> Hi John, > >>> >> >> > >>> >> >> I'm 56 and was diagnosed with PD in 2000, I've been taking > > Azilect > >>> >> >> and > >>> >> >> Requip (Ropinirole) the nausea form the Requip is unbearable. > >>> >> >> I > >> have > >>> >> >> introduced to my regimen for the past 5 months or so, > 'MaxGXL', > > a > >>> >> > supplement > >>> >> >> developed here in the US, by a US scientist and sold by a US > >>> >> >> company. It raises thet levels of GSH in your cells naturally. > >>> >> >> It > >>> >> >> took > >>> >> >> the > >>> >> >> GXL about a week to work on my sleeping pattern, I was waking > >>> >> up > >> 2-3 > >>> >> >> times > >>> >> >> during the night, now I sleep straight thru the night, and it > > took > >>> > about > >>> >> >> three weeks to work on my cognitive process but it was so > > subtle > >>> >> >> I > >>> > barely > >>> >> >> thought it was the GXL. I wasn't having problems looking for > > words > >> to > >>> >> > finish > >>> >> >> a sentence, my memory is back, I don't lose things around the > >> house, > >>> > I > >>> >> > have > >>> >> >> more energy and I feel good and my wife is happier. It is > >>> >> >> strange, > >>> > when > >>> >> >> I > >>> >> >> asked my doctor about it he said Gluta what? it seems the > >>> >> medical > >>> >> > community > >>> >> >> is keeping the use of Glutathione (GSH) under wraps, they > don't > >> want > >>> >> >> competition... I order mine from www.maxgxl.com/133282 I > >>> >> >> suggest > >>> >> >> getting > >>> >> >> as much info as possible of GSH, I went to www.youtube.comand > >>> > searched > >>> >> > for > >>> >> >> 'The mother of all antioxidants', there is this doctor Mark > >>> >> >> Hyman > >> who > >>> >> >> explains in details about GSH; excellent video. > >>> >> >> > >>> >> >> Good luck to you. > >>> >> >> > >>> >> >> Ernesto, > >>> >> >> Miami, FL > >>> >> >> > >>> >> >> On Sat, May 2, 2009 at 11:46 AM, john emrys > >> <[log in to unmask]> > >>> >> > wrote: > >>> >> >> > >>> >> >> > Hey John > >>> >> >> > > >>> >> >> > I've been on Amantadine since being diagnosed in October > of > >>> >> last > >>> > year; > >>> >> >> > dosage has remained constant and titrated from 100mg to > 300mg > >>> >> >> > per > >>> > day, > >>> >> > over > >>> >> >> > an initial period of 3 weeks. > >>> >> >> > > >>> >> >> > I space the dosing about 5-ish hours apart; I've found if > the > >> final > >>> >> >> > dose > >>> >> > of > >>> >> >> > 100mg is taken later than 8PM, I have trouble sleeping > >>> >> >> through > >> the > >>> >> > night. > >>> >> >> > > >>> >> >> > It does give me an energy boost and some minor relief from > >> muscle > >>> >> >> > tightness, but does nothing to improve gait or reduce > tremor. > >> It's > >>> > sort > >>> >> > of > >>> >> >> > just a little bit of "gas" for your "engine." > >>> >> >> > > >>> >> >> > On the other hand, I find it causes auditory hallucinations, > >>> >> >> > drowsiness, > >>> >> >> > occasional vertigo, foggy thought processing and swelling > > around > >>> > the > >>> >> > knees. > >>> >> >> > > >>> >> >> > I find much better results on GSH and mucuna bean, which I > >> started > >>> >> >> > about > >>> >> > 6 > >>> >> >> > months ago (the mucuna has been a very recent thing, so > it's > >>> >> >> > been > >>> > too > >>> >> > early > >>> >> >> > to tell – but so far, I'm definitely impressed). My neuro > >>> > practically > >>> >> > lit > >>> >> >> > his own hair on fire when I told him, but he couldn't deny > > the > >>> > results > >>> >> > of > >>> >> >> > the GSH. > >>> >> >> > > >>> >> >> > The goal is to be able to cut the amantadine by 35 - 50% > > within > >>> >> >> > 6 > >>> >> > months. > >>> >> >> > My view is the longer I stay away from starting the > agonists, > >> the > >>> >> > better. > >>> >> >> > > >>> >> >> > Hope that helps. > >>> >> >> > > >>> >> >> > > >>> >> >> > > >>> >> >> > Joh > >>> >> >> > > >>> >> >> > > >>> >> >> > >>> > >>> >> > > > ---------------------------------------------------------------------- > >>> >> >> > To sign-off Parkinsn send a message to: mailto: > >>> >> >> > [log in to unmask] > >>> >> >> > In the body of the message put: signoff parkinsn > >>> >> >> > > >>> >> >> > >>> >> > >>> >> >> > >>> > ---------------------------------------------------------------------- > >>> >> >> To sign-off Parkinsn send a message to: > >>> >> > mailto:[log in to unmask] > >>> >> >> In the body of the message put: signoff parkinsn > >>> >> > > >>> >> > >> > ---------------------------------------------------------------------- > >>> >> > To sign-off Parkinsn send a message to: > >>> >> > mailto:[log in to unmask] > >>> >> > In the body of the message put: signoff parkinsn > >>> >> > >>> > >>> >> > > > ---------------------------------------------------------------------- > >>> >> To sign-off Parkinsn send a message to: > >>> > mailto:[log in to unmask] > >>> >> In the body of the message put: signoff parkinsn > >>> &> > >>> > >>> > > ---------------------------------------------------------------------- > >>> > To sign-off Parkinsn send a message to: > >>> mailto:[log in to unmask] > >>> > oronto.ca > >>> > In the body of the message put: signoff parkinsn > >>> > > >>> > > >>> > > >>> > > >>> > **************Remember Mom this Mother's Day! 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