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Jim,

"PD is rare in that the body can affect the medication, as well as the other
way around."

Such an interesting statement, Could you say more about that?

Kathleen

2009/6/10 rayilynlee <[log in to unmask]>

> I did not write this article, have anything to do with  the research, nor
> am I passing judgment on the conclusion of this study, just reporting.
>
> Ray
>
> Rayilyn Brown
> Director AZNPF
> Arizona Chapter National Parkinson Foundation
> [log in to unmask]
>
> --------------------------------------------------
> From: "Jim Slattery" <[log in to unmask]>
> Sent: Tuesday, June 09, 2009 9:41 PM
> To: <[log in to unmask]>
> Subject: Re: Mouse Model points to new PD Treatments
>
>  From: "rayilynlee" <[log in to unmask]>
>> Subject: Mouse Model points to new PD Treatments
>>
>> Hi Rayilynlee,
>>
>> No non-human model of PD can ever produce the effects of psychological
>> stress on PD, since no non-human can produce the complex intermix of stress
>> hormones, personal reaction to incidents of stress, and the admix of
>> individual medications.
>> Nor can a non-human produce the conversions of  the catecholamine system,
>> particularly from dopamine to adrenaline (epinephrine) to nor-adrenaline
>> (nor-epinephrine) that can occur in a human subjected to psychological
>> stress. (Note for example, a PWP confronted with the need to make a public
>> presentation).
>>
>> High catecholamine levels in blood are associated with stress, which can
>> be induced from psychological reactions or environmental stressors such as
>> elevated sound levels, intense light, or low blood sugar level. PD is rare
>> in that the body can affect the medication, as well as the other way around.
>>
>> That said, any advance is for the better.
>>
>> Dr James F Slattery, PhD Soc Sc
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