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from Viartis:

3rd July 2009 - New research
THE LACK OF CENTENARIANS WITH PARKINSON'S DISEASE
Journal of Rural Health [2009] Summer; 25 (3) : 320-325 (Kaye J, Michael Y, 
Calvert J, Leahy M, Crawford D, Kramer P.) Complete abstract

In America alone, there are over 50,000 people over the age of 100. It is 
widely claimed that the likelihood of Parkinson's Disease increases with 
age, almost as if it is an age related deterioration. In contradiction of 
this assumption, the current study found that in centenarians (those over 
100 years old) Parkinson's Disease was rarely found, thereby nullifying the 
assumption of Parkinson's Disease being age related. It was also recently 
found that Parkinson's Disease started to become less likely at 90 years of 
age onwards. For the details click here.  However, some degree of dementia 
did become the norm in centenarians. Dementia is far more related to age. 
Over 60% of centenarians were found to have dementia, and nearly 90% were 
found to have at least some degree of impairment. Only around 10% of 
centenarians were found to be without dementia to some extent. In order to 
refer to this article on its own click here.

                                                                             
                                                                     30th 
June 2009 - New research
COMPARISON OF DBS SURGERY METHODS FOR TREATING PARKINSON'S DISEASE
Around 25% of Annals of Neurology [2009] 65 (5) : 586-595 (Okun MS, 
Fernandez HH, Wu SS, Kirsch-Darrow L, Bowers D, Bova F, Suelter M, Jacobson 
CE 4th, Wang X, Gordon CW Jr, Zeilman P, Romrell J, Martin P, Ward H, 
Rodriguez RL, Foote KD.) Complete abstract

Deep Brain Stimulation (DBS) involves the use of electrodes that are 
implanted into the brain and connected to a small electrical device called a 
pulse generator that can be externally programmed. DBS can reduce the need 
for L-dopa and related drugs.  For more information go to Deep brain 
stimulation. The two most common sites in the brain used for Deep Brain 
Stimulation (DBS) are the subthalamic nucleus (STN) and the globus pallidus 
interna (GPi). This study compared the effects of the two main types of DBS. 
There was no difference between the two methods in physical movement on the 
main Parkinson's Disease score (the UPDRS). The effect on mood and 
intellectual function was similar for both methods. Worsening of verbal 
fluency was seen in STN. The deterioration in verbal fluency in the off STN 
DBS state was suggestive of a surgical effect rather than due to the 
stimulation. Adverse mood effects occurred in both types. The direction of 
the surgical method (either optimal, dorsal or ventral) also had effect, as 
subjects in both types were less happy, less energetic and more confused 
when stimulated ventrally. In order to refer to this article on its own 
click here.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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