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Ray

New Technology Helps Parkinson's Patients Speak Louder

ScienceDaily (Aug. 25, 2009) - Researchers have developed a new technology 
that helps Parkinson's patients overcome the tendency to speak too quietly 
by playing a recording of ambient sound, which resembles the noisy chatter 
of a restaurant full of patrons.

"People with Parkinson's disease commonly have voice and speech problems," 
said Jessica Huber, an associate professor in Purdue's Department of Speech, 
Language and Hearing Sciences. "At some point in their disease they will 
have some form of voice or speech disorder that generally occurs a little 
later in the disease."

Parkinson's affects 1.5 million people in the United States and is one of 
the most common degenerative neurological diseases. About 89 percent of 
those with Parkinson's have voice-related change, which is related to how 
loudly they speak, and about 45 percent have speech-related change, or how 
clearly they speak.

"A major therapy is to get people to speak louder, which also may cause them 
to articulate more clearly," Huber said.
The most common therapy, the Lee Silverman voice treatment program, trains 
patients to speak louder in one-hour sessions four days a week for a month.

"Some Parkinson's patients do great with this approach, but others do not," 
Huber said. "They forget to keep speaking louder the minute they have left 
the therapy room. Lee Silverman tends to work less for people with later 
stages of disease or those who have some cognitive decline. So I wanted to 
know whether there was an easier way to cue people during therapy, rather 
than telling them, 'Try to be twice as loud,' or 'Try to focus on this sound 
meter and achieve this loudness.'"

Huber used a new approach: The patients were asked to speak louder while a 
recording of background "multitalker babble noise" was played. The noise is 
essentially the sound of a restaurant full of patrons, but without the 
clattering silverware and clinking glasses.
"They had an easier time getting louder when I had the noise in the room," 
she said. "Ordinarily, when I asked them to be twice as loud they would say 
they couldn't. They couldn't speak 10 decibels louder, but when I turned on 
the babble noise, they spoke over 10 decibels louder."
T    he background sound elicits a well-known phenomenon called the Lombard 
effect, a reflex in which people automatically speak louder in the presence 
of background sound.

"You go into a loud room at a party and you talk louder without even 
realizing it," Huber said. "We've all had the experience where the room 
suddenly gets quiet and you're still shouting but you didn't know you were."

Huber created a new electronic technology using this principle. The 
voice-activated device automatically plays the background babble when the 
person begins to speak. A sensor placed on the neck detects that the person 
has begun to speak and tells the device to play the babble through an 
earpiece worn by the patient.

"I got the idea that if we train them with a natural cue in their everyday 
environment, we will probably get better results," she said. "We ask them to 
wear the system for about four hours a day as they go about their daily 
routine."

A critical part of the research is to integrate the voice-detection sensor, 
called an accelerometer, developed in work led by biomedical engineering 
doctoral students Matias Zanartu and Julio C. Ho and biomedical engineering 
professor George Wodicka, head of Purdue's Weldon School of Biomedical 
Engineering.

"This sensor is crucial because it is essential that the background babble 
noise only turn on when the subject talks," Huber said.
The device prototype was built by engineering resources manager Jim Jones 
and senior research engineer Kirk Foster, both in the Weldon School. An 
earlier prototype had been built by Scott Kepner, manager of technical 
services, and Derek Tully, assistant manager of technical services, both in 
the Department of Speech, Language and Hearing Sciences.

Six patients wore the portable system for eight weeks. Data collected showed 
the system effectively prompts Parkinson's patients to speak louder and more 
clearly.

"Their speech changes significantly," said Huber, who is working with Meghan 
Darling, a doctoral student in Speech, Language and Hearing Sciences. "There 
have been times where I have called patients and they've had the device on 
and I didn't really recognize them. And these are patients I've known for a 
long time. This is beneficial also because it trains them in their everyday 
environment - in their homes, with their spouses, in their churches, in 
their social groups."

Huber determined the system works by measuring how much louder patients 
talked while on the device and without the device after eight weeks of 
training.

The researchers also are interested in examining the physiological changes 
elicited by the device. Patients wear a mask and sensors in elastic bands 
placed around the rib cage to precisely recording respiratory, laryngeal and 
articulatory data.

"We know the lung volume, and we know the pressure and the airflow they 
generate during speech, which tells us not only whether they are talking 
louder but how they are talking louder," Huber said. "For example, maybe 
they are using solely the respiratory system to get louder, or maybe it's 
all about the larynx."

The researchers also will test how well the system works by having people 
who are not speech pathologists listen to the patients pronouncing words 
that could be easily confused with other words.

Researchers will work in the future with patients at the Rehabilitation 
Institute of Indianapolis. Further research is needed to determine whether 
patients continue speaking louder when they are not wearing the device. The 
system could be further developed to use rechargeable batteries, Huber said.

The research is funded by the National Institutes of Health. Purdue has 
filed a provisional patent on the concept.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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