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This is not an advertisement. I have had difficulties with constipation. When you consider that to pass a motion, the Central Nervous System (CNS) has to send a complex series of messages to the rectum and subsidiary tissue in the correct sequence, and that PD is very good at ruining the flow of signals to smooth muscle (e.g. intestinal wall) as well as to striated muscle (e.g. leg muscles), it is no wonder that constipation is an ongoing concern for people with PD. I have been prescribed a very good aid by my G.P. I won't mention the brand name, and I have no commercial interests in the product. This product recognises that to effectively treat constipation in PD, you need both a purgative to stimulate evacuation, combined with a faecal softener to facilitate movement. This product has both, and is rather more gentle than proprietary products I have tried. This product contains Macrogol, which is the International Non-proprietary Name (INN) for polyethylene glycol. It also contains sodium chloride, sodium bicarbonate, and potassium chloride, to maintain a correct balance of electrolytic salts in the system. It also contains potassium acesulfame, a calorie-free sweetener. It comes as a powder in a 13.8g sachet, which is dissolved in 125 mL of water. Dosage is 1 to 3 sachets daily, as required. Supply is on doctor's prescription only. It can be used to cure faecal impaction as diagnosed by a doctor, at up to 8 sachets in one day. Works for me. Jim ------------------------- NB:This is not a medical recommendation, but only the opinion of the writer. Persons should not change their medication regimen without first consulting their personal physician. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn