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Its effect is on the brain intrathecally. It sits in the spinal fluid in the brain until used up. On Sep 4, 2009, at 12:22 PM, mschild wrote: > I didn't know baclofen was still used but why not? Its main use is > as an antispasmodic particularly for end of dose dyskinesias. Not > clear if its effect is spinal or encephalic. I have no idea about > dosage, sorry > maryse > > Subject: Baclofen > > >> I have been taking Baclofen for painful dystonia in my foot. Since >> Sinemet >> acts against >> dystonia, I could have increased my Sinemet intake but I do that very >> reluctantly. Little by >> little over the past two years, I have been increasing my daily >> Baclofen >> intake. The Neuro who prescribed it is a competent Neuro but not a >> Movement >> Disorder Specialist. He told me what he considers a max daily dose >> to be >> (however I split it up). Are there any informed opinions as to >> maximum daily >> dose. I'll reveal his answer after any answer stream here >> stops. I don't want to influence any (if any), answers. >> >> Paul >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn