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Baclofin is typically used for spasticity which is hypertonia but very different than rigidity that is a PD symptom. It is atypical to apply baclofin to PD. The typical max dose for baclofin is 80 mg daily. Sent from my iPhone On Sep 5, 2009, at 2:44 AM, Pamela Clifton <[log in to unmask]> wrote: > Its effect is on the brain intrathecally. It sits in the spinal > fluid in the brain until used up. > On Sep 4, 2009, at 12:22 PM, mschild wrote: > >> I didn't know baclofen was still used but why not? Its main use is >> as an antispasmodic particularly for end of dose dyskinesias. Not >> clear if its effect is spinal or encephalic. I have no idea about >> dosage, sorry >> maryse >> >> Subject: Baclofen >> >> >>> I have been taking Baclofen for painful dystonia in my foot. Since >>> Sinemet >>> acts against >>> dystonia, I could have increased my Sinemet intake but I do that >>> very >>> reluctantly. Little by >>> little over the past two years, I have been increasing my daily >>> Baclofen >>> intake. The Neuro who prescribed it is a competent Neuro but not a >>> Movement >>> Disorder Specialist. He told me what he considers a max daily dose >>> to be >>> (however I split it up). Are there any informed opinions as to >>> maximum daily >>> dose. I'll reveal his answer after any answer stream here >>> stops. I don't want to influence any (if any), answers. >>> >>> Paul >>> >> >> --- >> ------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: mailto:[log in to unmask] >> In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn