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9th September 2009 - New research THE EFFECT OF ROPINIROLE (REQUIP) ON PARKINSON'S DISEASE Clinical neurology and neurosurgery [2009] Sep 2 [Epub ahead of print] (Valldeoriola F, Cobaleda S, Lahuerta J.) Complete abstract Ropinirole is a dopamine agonist that is commonly used in the treatment of Parkinson's Disease. It is often sold as Requip, Ropark, or Adartrel. For more information go to Ropinirole. Ropinirole was found to be mostly used as an add on treatment (in 76% of cases), and as the only treatment in around a quarter (24%) of those people using it. The average maintenance dose was found to be 9mg per day, and normally be within the range 4mg to 15mg. Over a quarter (28%) of people taking Ropinirole reported adverse reactions. The most frequent adverse reactions were somnolence and sedation (9%), gastrointestinal symptoms (7%), increase in dyskinesia (6%), and orthostatic symptoms (4%). Treatment using Ropinirole was withdrawn in 14% of patients, largely because of either adverse reactions, lack of efficacy, or change in treatment. Over 80% of people taking Ropinirole were considered by their neurologists to have improved after taking it. In order to refer to this article on its own click here. 5th September 2009 - New research RETINAL STEM CELLS DISAPPEAR AFTER SURGERY FOR PARKINSON'S DISEASE Neurology [2009] Sep 2. [Epub ahead of print] (Farag ES, Vinters HV, Bronstein J.) Complete abstract Retinal pigment epithelial cells have been found to disappear after being used in a form of surgery intended for use in Parkinson's Disease. For years, the use of implanted stem cells have been claimed to have the potential to rid Parkinson's Disease. One of these means is the use of RPE (retinal pigment epithelium) cells. These cells are found in the eyes and can also produce dopamine, the substance whose deficiency causes Parkinson's Disease. A 68-year-old man underwent surgical implantation of 325,000 RPE cells in Spheramine (gelatin microcarriers) for the treatment of Parkinson's Disease. He happened to die six months after the surgery took place. This enabled the researchers to see what happened to retinal stem cells after surgical implantation. Over 99.9% of the cells had disappeared after only six months. Implanted cells simply failed to survive. A previous study using the same methods demonstrated only a moderate benefit for six months. For more details see the Complete abstract. Despite different forms of stem cell surgery now being carried out in countries around the world, there is not even one study in the entire medical literature showing that anybody has ever been rid of Parkinson's Disease by this means. In order to refer to this article on its own click here. Rayilyn Brown Director AZNPF Arizona Chapter National Parkinson Foundation [log in to unmask] ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn