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Sami et al, Re: Requip: I have been taking Requip (ropinerole) for 7 years or so, and I finally quit the stuff last week. I just could not take the continual exhaustion and sleepiness which overtook me daily, so I went to my neuro and he took me off it. I was last on a dose of 3mg 3 times a day and have been on doses greatly varying from this level. I don't know what implications I will unearth, but two things have happened since my Dr.'s visit: 1) Sleepiness hasn't overtaken me mid-day, and my energy level has increased 2) Despite an increase of Stalevo from 50 to 100mg times 3 per day, my tremors have noticeably become stronger. I used to tolerate unheard of amounts of requip, and now I can't imagine...kind of like my career as a pot smoker. Frankly, my dears, I don't give a damn about the twitch if I can stay awake and alert. And Sami, I have given up on organizing or clearing my 'in box'! Hopefully I won't delete my million dollar prize! Enjoy! Rick McGirr -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of Sami Sent: Wednesday, September 16, 2009 7:01 AM To: [log in to unmask] Subject: Re: Effect of Requip on PD As you can see, I am way behind in reading my mail. Carl, It never hurts to check the e-mails before you delete them. There may just be something in one of them that can help and don't we all need that little boost that's in the e-mail that you accidently delete? Sami From: carl grame Date: 9/13/2009 11:00:23 PM To: [log in to unmask] Subject: Re: Effect of Requip on PD I do delete all of them but that takes time. Is there any other option? On Sat, Sep 12, 2009 at 4:31 AM, Kathleen Cochran <[log in to unmask]> wrote: > If you don't want to read it, delete it. End of story. > > 2009/9/11 carl grame <[log in to unmask]> > >> I don't look at any of your emails, there are just too many from you. >> What else do you do? >> >> On Thu, Sep 10, 2009 at 8:43 PM, rayilynlee <[log in to unmask]> wrote: >> > 9th September 2009 - New research >> > THE EFFECT OF ROPINIROLE (REQUIP) ON PARKINSON'S DISEASE >> > >> > Clinical neurology and neurosurgery [2009] Sep 2 [Epub ahead of print] >> > (Valldeoriola F, Cobaleda S, Lahuerta J.) Complete abstract >> > >> > Ropinirole is a dopamine agonist that is commonly used in the treatment >> of >> > Parkinson's Disease. It is often sold as Requip, Ropark, or Adartrel. For >> > more information go to Ropinirole. Ropinirole was found to be mostly used >> as >> > an add on treatment (in 76% of cases), and as the only treatment in >> around a >> > quarter (24%) of those people using it. The average maintenance dose was >> > found to be 9mg per day, and normally be within the range 4mg to 15mg. >> Over >> > a quarter (28%) of people taking Ropinirole reported adverse reactions. >> The >> > most frequent adverse reactions were somnolence and sedation (9%), >> > gastrointestinal symptoms (7%), increase in dyskinesia (6%), and >> orthostatic >> > symptoms (4%). Treatment using Ropinirole was withdrawn in 14% of >> patients, >> > largely because of either adverse reactions, lack of efficacy, or change >> in >> > treatment. Over 80% of people taking Ropinirole were considered by their >> > neurologists to have improved after taking it. In order to refer to this >> > article on its own click here. >> > >> > 5th September 2009 - New research >> > RETINAL STEM CELLS DISAPPEAR AFTER SURGERY FOR PARKINSON'S DISEASE >> > >> > Neurology [2009] Sep 2. [Epub ahead of print] (Farag ES, Vinters HV, >> > Bronstein J.) Complete abstract >> > >> > Retinal pigment epithelial cells have been found to disappear after being >> > used in a form of surgery intended for use in Parkinson's Disease. For >> > years, the use of implanted stem cells have been claimed to have the >> > potential to rid Parkinson's Disease. One of these means is the use of >> RPE >> > (retinal pigment epithelium) cells. These cells are found in the eyes and >> > can also produce dopamine, the substance whose deficiency causes >> Parkinson's >> > Disease. A 68-year-old man underwent surgical implantation of 325,000 RPE >> > cells in Spheramine (gelatin microcarriers) for the treatment of >> Parkinson's >> > Disease. He happened to die six months after the surgery took place. This >> > enabled the researchers to see what happened to retinal stem cells after >> > surgical implantation. Over 99.9% of the cells had disappeared after only >> > six months. Implanted cells simply failed to survive. A previous study >> using >> > the same methods demonstrated only a moderate benefit for six months. For >> > more details see the Complete abstract. Despite different forms of stem >> cell >> > surgery now being carried out in countries around the world, there is not >> > even one study in the entire medical literature showing that anybody has >> > ever been rid of Parkinson's Disease by this means. In order to refer to >> > this article on its own click here. >> > >> > Rayilyn Brown >> > Director AZNPF >> > Arizona Chapter National Parkinson Foundation >> > [log in to unmask] >> > ---------------------------------------------------------------------- >> > To sign-off Parkinsn send a message to: mailto: >> [log in to unmask] >> > In the body of the message put: signoff parkinsn >> > >> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: mailto: >> [log in to unmask] >> In the body of the message put: signoff parkinsn >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] ca > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ____________________________________________________________ No virus found in this incoming message. 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