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Black Americans newly diagnosed with Parkinson's disease are a quarter as 
likely as whites to walk out of their first office visit with a prescription for 
anti-PD treatment, according to a new study.

Researchers identified new diagnoses of PD from Medicaid records in 
Pennsylvania between 1999 and 2003, excluding patients with possible secondary 
parkinsonism, as well as those who received anti-PD treatments in the prior 12 
months. Of the 307 identified cases, 264 were white and 43 were black. Compared 
to historical averages for all PD patients, patients in this study were 
somewhat younger (mean age 55) and more likely to be female (61%), but there 
were no significant differences in these variables between blacks and whites. 
The initial visit was with a neurologist for 33% of blacks and 39% of whites 
(difference not significant); about 90% of both groups were eligible for 
Medicaid because of a disability; and blacks were more likely to receive care 
in an urban setting compared to whites (p<0.0001).

Thirty-four percent of patients received a prescription for anti-PD medication 
or physical therapy at their first office visit, but the rates differed by race: 
12% of blacks and 38% of whites received prescriptions. The odds ratio for 
receiving a prescription was 0.24 (95% confidence interval 0.09-0.64) for 
blacks. The two groups had about equal rates of six-month follow-up 
appointments. 

The authors point out that the sample was relatively young, poor, and 
disabled, and that "multiple comorbid conditions that require treatment may 
discourage clinicians from adding therapies with potential cross-
interactions," potentially affecting the generalizability of the results to the 
larger population.

"Our data cannot explain whether differences in treatment were due to 
differences in provider recommendations or differences in patient acceptance of 
treatment," the authors note. "Understanding the underlying causal mechanisms 
of these racial disparities such as patient and physician preferences, 
patient-physician communication, and confounding socioeconomic differences is 
important to develop interventions to reduce inequities in care and improve 
health for all patients with PD."

Treatment disparities in Parkinson's disease
N Dahodwala, M Xie, E Noll, A Siderowf, DS Mandell
Ann Neurol 2009;66:142-145

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