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For those who don’t know or are curios: An agonist is a biochemical assists a particular therapy drug reaction within the body Ant-agonist is a biochemical that retard the therapy drug from reacting An enzyme is a biochemical catalyst that speeds up or slows down particular process whilst not being consumed in this process A co enzyme assists the enzymatic process however dependent upon other needs may be consumed in the process. As the purpose of any therapy treatments invokes the use of all or some of these components, there must be a warning against overuse of MAO A and B reagents i.e. that perform overall process. Hope this simplifies an otherwise complex subject John Thomas BAps MR -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of mschild Sent: Tuesday, November 03, 2009 11:20 PM To: [log in to unmask] Subject: Re: Warning re Rotigotine patches - > I suspect it worked too well and relaxed a muscle that was already too > loose. since rotigotine is an agonist, I wasn´t aware it could have a topical myorelaxing effect maryse ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn