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Hi, My name is Robert from Australia. My father received significant head injuries in a road accident in 2002. After rehabilitation he managed to slowly recover for a few years, but the last 5 years he has developed all the cardinal symptoms of Parkinsons disease, and over the last 6 months in particular these symptoms have progressed to such a stage that my father's quality of life has seriously diminished. In 2005 we tried Sinimet but there was zero response. It seems, like most cases of atypical Parkinsons, that the dopa receptors were not spared. I am desperately looking for treatments that may atleast modestly relive some of my fathers symptoms. Even a 10% would make a huge difference for us. (1) In one weeks time we will see our doctor for botox injections. At this stage I suspect that the injections will be in the calf muscles, but if anyone can suggest sites of injection to assist with dystonia, I would really appreciate it. (2) A week later we will be seeing a neurologist for trial of pharmacological medications to hopefully assist. I know most neurologist would not even bother, given the low response rate for atypical Parkinsons, but I have my fingers crossed. I have read of some success with atypical parkins and the Dopamine receptor agonist called bromocriptine, and am hopeful that my father can trial this. I have also read about the transdermal administration of rotigotine, and would be asking about this too. I am however looking for any other pharmacological suggestions for atypical parkinsons, with some science behind them, to suggest to the neurologist as a trial. Can anyone help me? Thanks Robert ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn