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I've taken Mirapex for more than a year now and it seems effective for night cramps and restless leg. I only take one at night, however; if I take one in the morning it makes me drowsy. I also take Sinemet and Azilect. Principle side effects are occasional "active" dreams. I should also note that my physical therapist taught me to do hamstring stretches before bed each night and that _really_ seems to help the restless leg. (Balls of feet on a step, moving heels up and down slowly.) I've also discovered that leg cramps can be moderated by drinking more water in the daytime, before 6 p.m. (After 6 and the expected happens.) Alf -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of Mary Ann Ryan Sent: Sunday, April 25, 2010 9:01 AM To: [log in to unmask] Subject: Re: Mirapex? Mirapex can have terrible side effects. But.....it did stop Jamie's terrible tremor and muscle cramps. We kept him on one tablet a day until the day he died. It may be that the compulsions that occur at higher doses can be managed at lower doses that still positively impact symptoms. ------- Mary Ann (CG Jamie 68/28 with PD, died 11/20/07) www.bentwillowfarm.org ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn