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FWD from Clinicaltrials.org Tel: (212) 923-4700 | (800) 457-6676<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /> www.pdf.org Parkinson's Clinical Research Newsletter ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ April 2010 www.PDtrials.org ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Greetings! Thank you for signing up to receive the PDtrials Parkinson's Clinical Research Newsletter. This regular email newsletter provides you with information on Parkinson's disease (PD) clinical trials that are actively looking for participants, as well as news on Parkinson's research and treatments. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The Sure-PD Study: Unsuccessful Research Leads to Promising Study by Dr. Michael A. Schwarzschild and Dr. Alberto Ascherio Parkinson's disease (PD) patients are sometimes reluctant to participate in experimental drug trials because there is no guarantee of personal benefit from a study drug, or even of receiving the study drug rather than placebo. Others have no problem with these uncertainties because for them the personal benefit comes from knowing they are contributing to the discovery of new treatments that may help all people suffering from the disease. Yet even these "big picture" individuals can be discouraged from volunteering for demanding clinical research by the reality that any given drug trial faces long odds in the quest to establish a breakthrough treatment. However, it should not be overlooked that studies that may seem to have failed at the time can provide unexpected and highly valuable data that can open doors to new ways of exploring PD. Continue [http://www.pdtrials.org/en/clinical_research_news/release/pr_1272299623] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ New Clinical Trials The Effects of the Rivastigmine Patch on Parkinson's Disease When Associated with Memory and/or Thinking Problems This twelve week study will investigate the effects of the rivastigmine patch on attention and behavior in people with Parkinson's disease when associated with memory and/or thinking problems. This is an open label study, meaning that there is no placebo and everyone will receive the medication. Learn more. [http://www.pdtrials.org/en/browse/all/view/282] Study of the Effects of a Computer-Style Rehabilitation Program on Movement Symptoms of Parkinson's Disease People with Parkinson's disease often have difficulty with motor planning, such as initiating or starting movements. To investigate effective methods of addressing such symptoms, this study will test a computer game-style rehabilitation program for people with PD. The investigator believes that the program will improve performance on a movement initiation task as well as on activities of daily living, such as walking, preparing a meal or opening a medicine bottle. Learn more. [http://www.pdtrials.org/en/browse/all/view/281] Study of the Effects of Droxidopa in People Who Show Symptoms of Neurogenic Orthostatic Hypotension Blood pressure normally decreases in healthy individuals upon standing. The mechanisms that regulate blood pressure upon standing are dysfunctional in people with orthostatic hypotension (OH), a condition that may lead to inadequate blood flow to the brain (cerebral perfusion) with accompanying symptoms including brief loss of consciousness (syncope), dizziness or lightheadedness, unsteadiness and blurred or impaired vision. This study will measure the efficacy of the drugh droxidopa on symptoms of neurogenic orthostatic hypotension in participants. Learn more. [http://www.pdtrials.org/en/browse/all/view/280] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Join Our Monday, May 10 Educational Webinar on How Completed Studies Shape the Future Monday, May 10, 2010 at 2 PM ET Led by Bernard Ravina, M.D., M.S.C.E Join PDtrials - by phone or online - for "Lessons Learned: How Completed Parkinson's Clinical Studies Help Shape the Future." The one-hour webinar (online seminar) will be led by Bernard Ravina, M.D., M.S.C.E., who will discuss how the research community and people with Parkinson's benefit from unsuccessful clinical studies. Dr. Ravina will explain the ways that these Parkinson's trials help shape both the scientific questions and design of future studies. Continue [http://www.pdtrials.org/en/educ_webinars] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Have You Participated in a Parkinson's Clinical Study? Join the Partners in Progress Honor Roll Today! If you have participated in a Parkinson's clinical study, we'd like to recognize your very personal commitment to help move Parkinson's clinical research forward by providing you with a PDtrials baseball cap as a token of our thanks and adding you to our Partners in Progress Honor Roll. Take a look at our Honor Roll of participants here [http://www.pdtrials.org/en/partners_in_progress], and if you would like to be included, contact us at [log in to unmask] today! Find us on Facebook http://www.facebook.com/pages/PDtrials/67722674992 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ PDtrials is led by Parkinson's Disease Foundation [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.pdf.org%2F&id=preview] In collaboration with: APDA [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.apdaparkinson.org%2Fuser%2Findex.asp&id=preview] FOX [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.michaeljfox.org%2F&id=preview] National Parkinson Foundation [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.parkinson.org%2Fsite%2Fpp.asp%3Fc%3D9dJFJLPwB%26b%3D71117&id=preview] Parkinson's Action Network [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.parkinsonsaction.org%2F&id=preview] PA Logo New [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.parkinsonalliance.org%2F&id=preview] We Move [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.wemove.org%2F&id=preview] PDtrials is advised by: National Institutes Of Health [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.nih.gov%2F&id=preview] The Parkinson's Institute [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.thepi.org%2Fsite%2Fparkinson&id=preview] Parkinson Pipeline Project [http://r20.rs6.net/tn.jsp?t=bmb6esdab.0.0.zle7tnbab.0&ts=S0480&p=http%3A%2F%2Fwww.pdpipeline.org%2F&id=preview] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ © 2010 PDtrials. 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