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PhytoPharm  issued update on Cogane , "a novel small molecule, orally bioavailable neurotrophic factor inducer that readily crosses the blood brain barrier. In preclinical models, CoganeTM stimulates the release of neurotrophic factors and increases neurite outgrowth. Importantly, CoganeTM also reverses the decrease of neurotrophic factors and reverses dopaminergic neurnal degeneration observed in vitro.
see: http://www.phytopharm.com/parkinson-s-disease/
Also in their interrim report they announced they are planning for a multi-mational phase II trial to begin later this year.
see
http://www.phytopharm.com/assets/News-releases/Interims-HY-2010.pdf
The Parkinson PipelineProject has been following the progress of this treatment for a number of years and it seems very promising.  -- similar to GDNF in a pill!
Linda

www.pdpipeline.org


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