I am going to start next Monday with tai chi. I'm glad to hear that it helps. Haven't heard of requip but will check it out. take care, Karol
--- On Mon, 12/6/10, [log in to unmask] <[log in to unmask]> wrote:
From: [log in to unmask] <[log in to unmask]>
Subject: Re: Mirapex and going Solo Sinemet
To: "Karol Klim" <[log in to unmask]>
Date: Monday, December 6, 2010, 9:27 PM
We found that tai chi is very good too. Husband does the one where he s
its to do the exercises. Has helped tremendously.
He is on requip and sinemet and is doing good now. Dot cg Bill 75/67/65
-----Original Message-----
From: Karol Klim <[log in to unmask]>
To: PARKINSN <[log in to unmask]>
Sent: Mon, Dec 6, 2010 5:34 am
Subject: Mirapex and going Solo Sinemet
Yes, I agree with the keep moving. I saw that several people mentioned doing
crafts. I started an upholstery class yesterday and for three hours actually
totally forgot I had PD.
I am glad to see that you have had success with Mirapex and Sinemet. I am
contemplating cutting out Mirapex to see how I do solo. I want to use as little
meds as possible but still be able to do my routine and less routine affairs.
take care, Karol
--- On Sun, 12/5/10, [log in to unmask] <[log in to unmask]> wrote:
From: [log in to unmask] <[log in to unmask]>
Subject: Re: Mirapex and going Solo Sinemet
To: "Karol Klim" <[log in to unmask]>
Date: Sunday, December 5, 2010, 10:37 PM
I have been on Mirapex and SInament for about 5 years. Also take Azlect l in
the am. It all seems to keep me
going and not any great side effects. SOmetimes sleepy and insominia. But I am
a night owl. Need only about
7 hrs. DO water arobics twice a week. Just keep moving.
-----Original Message-----
From: haphill <[log in to unmask]>
To: PARKINSN <[log in to unmask]>
Sent: Sun, Dec 5, 2010 2:00 am
Subject: Re: Mirapex and going Solo Sinemet
I've been on Mirapexin for a couple of years- it gives me insomnia, which is
dd. no annoying hallucinations but the compulsions are a bit tiresome.
Quoting Karol Klim <[log in to unmask]>:
> Paul, Your comments agreed with my physician's explanation of why I am on
Mirapex. I am concerned though regarding the many possible side effects of
Mirapex. The list is long. I also am not driving as of now until I see
whether I have any issues with extreme drowsiness or sudden onset of sleep.
Attempted to get my physician to put sleep issues side effects down on his
letterhead and he would not do so for my employer. He listed all the other
side effects, compulsions and hallucinations, but strayed away from
indicating the sudden onset of sleep or extreme drowsiness issue. My
employer for now has been agreeable to me working at home.
I am just wondering how I would do if I came off Mirapex and kept at same
level of Sinemet. I started both at same time and therefore have no way to
judge how much more relief I am getting with Mirapex.
I would love to have any other resources or sites that you may have. I've
just been diagnosed at 53, although looking back think this has been going on
for about six years but I didn't know the source of problem. It started with
gastro problems and frozen right shoulder. I have seen about every
specialist until I finally got diagnosed.
take care, and thank you for the information. Karol
--- On Thu, 12/2/10, [log in to unmask] <[log in to unmask]> wrote:
From: [log in to unmask] <[log in to unmask]>
Subject: Re: Solo Sinemet
To: "Karol Klim" <[log in to unmask]>
Date: Thursday, December 2, 2010, 9:16 PM
Karol:
PD is very much a designer disease and although each of us will likely see
most of the symptoms eventually, they will show up at different times in
each of our disease progression's and affect each of us with different
intensities. The effect of the different medications available also varies
with
each individual although it is generally conceded that Sinemet is the 'gold
standard' addressing more symptoms for more people than any other. But it
has an eventual downside for most PWP and that is the onset of Dyskinesia
after an individual's drug limit is reached (observe Michael Fox for
example). This limit varies with everyone and I don't think it can be
pre-determined but for most PWP it takes a number of years of increasing
doses at ever
shortening intervals.
Mirapex is one of a family of drugs called Dopamine Agoniststs. Another
would be Requip. Both usually produce the same PD mitigation results but
sometimes have different side effects for different PWP's. I took Requip for
the first 5 years (as I recall) and quit because I had constant edema in my
legs. I am a PWP, not an MD so you have to take my rambling as being
unofficial, but it is my understanding that current practice is to start
with a
Dopamine Agonist to postpone or delay the start of Sinemet and stay with the
Agonist until something (side effect, inefficiency) requires you to switch
to Sinemet.
Here's some info from Wikipedia:
_Dopamine agonist - Wikipedia, the free encyclopedia_
(http://en.wikipedia.org/wiki/Dopamine_agonist)
The Parkinson List Serv is a good way to keep current. There are other
sites you can join at no cost to keep getting updated. Let me know if you
would
like a list
Paul
In a message dated 12/2/2010 02:00:19 Eastern Standard Time,
[log in to unmask] writes:
Karol
I don't take Sinemet at all. I had DBS in 2003 and that stopped the
tremors. Sinemet only helped on the first dose. I've tried it many times.
Took it when batteries died this summer so I could move a little, but
doesn't
seem to help at all now that my batteries have been replaced.
DBS is great for tremor; doesn't help all that much for balance,
bradykinesia, micrographia and makes voice worse, but its worth it to me. I
had
botox recently for leg dystonia but it doesn't seem to have helped. Some
people with PD find botox helpful for dystonia.
Ray
From: Karol Klim
Sent: Wednesday, December 01, 2010 3:55 AM
To: [log in to unmask]
Subject: Solo Sinemet
Hello, I am 53 years of age and have been recently diagnosed with PD and
am taking .75 of Sinemet and .75 of Mirapex. I would like to see how I
would do with just taking Sinemet alone. I am concerned about the side
effects
of Mirapex, particularly the "sudden onset of sleep" possibility while
driving. It sounds like you have had a lot of success with only taking
Sinemet at a very low dosage. Is this true or have you had some tremors and
rigidity? I would like to do the same, if possible. thanks for your
help.
Karol
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