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Nowacka B, LubiƄski W, Karczewicz D.

Department of Ophthalmology, Pomeranian Medical Academy in Szczecin. 
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Abstract

PURPOSE: Based on available literature, the authors describe the most frequent 
ocular diseases and symptoms, as well as bioelectrical dysfunction of the 
visual pathway in patients with Parkinson's disease (PD).

MATERIAL AND METHODS: Data published in literature available in PubMed 
library. The most often ocular diseases, symptoms and the bioelectrical 
dysfunction were diagnosed using routine ophthalmological examination 
including tear film tests, perimetry, optical coherence tomography (OCT), color 
and contrast sensitivity tests, and electrophysiological recordings like EOGs, 
flash, pattern and multifocal ERGs, VEPs.

RESULTS: The most frequent ocular diseases in PD are dry eye syndrome and 
glaucoma. At least 25% of PD patients manifest visual hallucinations. The most 
prominent bioelectrical dysfunction of the visual pathway was observed in 
outer layers of the retina (retinal pigmented epithelium, phoptreceptors) and 
it was registered mainly in EOG, PERG and mfERG tests.

CONCLUSIONS: During examination of PD patents, general ophthalmologists should 
especially pay attention to diagnosis and treatment of glaucoma and dry eye 
syndrome. In PD visual deficits may occur without any noticeable changes in the 
routine ophthalmological examination. Electrophysiological recordings can 
explain, at least partially, visual dysfunction in course of PD.

PMID: 21117366 [PubMed - indexed for MEDLINE]

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