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Small intestinal bacterial overgrowth has been found to be highly prevalent in 
Parkinson's Disease. Parkinson's Disease is associated with gastrointestinal 
motility abnormalities that could favour the occurrence of small intestinal 
bacterial overgrowth. The aim of this study was to assess the prevalence of 
small intestinal bacterial overgrowth in people with Parkinson's Disease. The 
prevalence of small intestinal bacterial overgrowth was far higher in people 
with Parkinson's Disease. It occurred in over half (54%) of all people with 
Parkinson's Disease, in contrast to only 8% of people that do not have 
Parkinson's Disease. The severity of Parkinson's Disease was also very 
significantly related to small intestinal bacterial overgrowth.

This can lead to the following symptoms : excess gas, abdominal bloating and 
distension, abdominal pain, and diarrhea or in some cases chronic 
constipation.The researchers suggest that the gastrointestinal motility 
abnormalities that often occur in Parkinson's Disease might explain this 
association.

Movement Disorders [2011] 26 (5) : 889-892 (Gabrielli M, Bonazzi P, 
Scarpellini E, Bendia E, Lauritano EC, Fasano A, Ceravolo MG, Capecci M, Rita 
Bentivoglio A, Provinciali L, Tonali PA, Gasbarrini A.) 

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