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In an article today in the San Antonio 
Express-News, a new theory was presented on why 
DBS works on the brain to relieve symptoms.


>Charles Wilson, a professor of neurobiology at 
>the 
><http://www.mysanantonio.com/?controllerName=search&action=search&channel=life%2Fhealth&search=1&inlineLink=1&query=%22University+of+Texas+at+San+Antonio%22>University 
>of Texas at San Antonio, studies the part of the brain affected by Parkinson's.
>
>Using some complicated mathematics to predict 
>how brain signals should normally ebb and flow 
>in the brain, he argues that the problem in 
>Parkinson's is that brain cells are a little too harmonious with one another.
>
>“One of the things we know for sure about 
>Parkinson's is that neurons that normally are 
>firing independently of each other in the basal 
>ganglia (the part of the brain that controls 
>movement) start to become correlated,” Wilson 
>said. Shooting electrical pulses into the brain 
>at a particular rate and frequency breaks up 
>that synchronized behavior ­ and eases symptoms, he said.
>
>
>Read more: 
><http://www.mysanantonio.com/news/local_news/article/Theory-is-offeredon-brain-treatment-1466834.php#ixzz1SCwuzq2Y>http://www.mysanantonio.com/news/local_news/article/Theory-is-offeredon-brain-treatment-1466834.php#ixzz1SCwuzq2Y 
>

According to conventional theory DBS shouldn't 
work but exacerbate the symptoms.

>“We have been practicing deep brain stimulation 
>now for over a decade ­ literally without 
>knowing what we're doing,” said Dr. 
><http://www.mysanantonio.com/?controllerName=search&action=search&channel=life%2Fhealth&search=1&inlineLink=1&query=%22Michele+Tagliati%22>Michele 
>Tagliati, director of the movement disorders 
>program at Cedars-Sinai Medical Center in Los 
>Angeles, who wasn't involved in the research but 
>praised the study. “We know we're doing right if 
>the patient gets better, but not everybody 
>responds. Knowing the methods of action better 
>might allow us to adapt strategies to difficult patients.”
>
>Read more: 
><http://www.mysanantonio.com/news/local_news/article/Theory-is-offeredon-brain-treatment-1466834.php#ixzz1SCxqpcAL>http://www.mysanantonio.com/news/local_news/article/Theory-is-offeredon-brain-treatment-1466834.php#ixzz1SCxqpcAL 
>


John Cottingham 

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