The current edition of The American Journal of Human Genetics reported some genetic correlation found for a biological cause of some neurological disorders, including Parkinson's disease. The family has tremor-predominant dopa-responsive parkinsonism with a mean onset of 50.6 ± 7.3 years. Below is the abstract and the full report may be purchased at the publishers site. For those with access to a nearby medical library, they probably have a subscription and you can read the edition free. An easier to read and understand article is at: http://tinyurl.com/causeofPD Copyright © 2011 The American Society of Human Genetics All rights reserved. The American Journal of Human Genetics, <http://www.cell.com/AJHG/issue?pii=S0002-9297(11)X0007-1>Volume 89, Issue 1, 162-167, 15 July 2011 doi:10.1016/j.ajhg.2011.06.001 >The identification of genetic causes for >Mendelian disorders has been based on the >collection of multi-incident families, linkage >analysis, and sequencing of genes in candidate >intervals. This study describes the application >of next-generation sequencing technologies to a >Swiss kindred presenting with >autosomal-dominant, late-onset Parkinson disease >(PD). The family has tremor-predominant >dopa-responsive parkinsonism with a mean onset of 50.6 ± 7.3 years. John Cottingham ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn