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Neurology [2011] Nov 2   [Epub ahead of print] (Y.A.Rajabally, J.Martey)  
Neuropathy has been found to be nearly seven times more prevalent in 
Parkinson's Disease. Neuropathy is the malfunction of nerves throughout the 
body. Neuropathy can cause a pins-and-needles sensation, numbness, burning 
pain, loss of vibration sense, and a loss of position sense, which is not 
knowing where the arms and legs are. Walking and even standing can become 
unsteady. The effects of neuropathy can progress to far more widespread and 
serious symptoms. For more information go to Polyneuropathy. The researchers 
found that Vitamin B12 deficiency was a more common cause of neuropathy. 
Vitamin B12 levels were found to be significantly lower in people with 
Parkinson's Disease. They believed that the Vitamin B12 deficiency in 
Parkinson's Disease could be related to the effect of long term use of L-dopa. 
They consequently suggested that both Vitamin B and Vitamin B12 monitoring and 
supplementation, as well as serial clinical assessment for neuropathy, may be 
advisable in people with Parkinson's Disease.

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