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> Date: Fri, 4 May 2012 13:25:40 +0200
> From: [log in to unmask]
> Subject: CAUSES OF SUDDEN WORSENING IN PARKINSON'S DISEASE
> To: [log in to unmask]
> 
> CAUSES OF SUDDEN WORSENING IN PARKINSON'S DISEASE
> 
> Neurologist [2012] 18 (3) : 120-124 (K.S..Zheng, B.J.Dorfman, P.J.Christos, 
> N.R.Khadem, C.Henchcliffe, P. Piboolnurak, M.J.Nirenberg) Complete abstract
> 
> Episodes of sudden and transient worsening of symptoms commonly occur in 
> Parkinson's Disease, especially when the Parkinson's Disease is more severe. A 
> quarter of people with Parkinson's Disease were found to be affected in this 
> way. Infection was the single most frequent cause, accounting for a quarter of 
> cases. Other common causes were anxiety, medication errors, poor adherence to 
> taking the required drugs, medication side effects, and postoperative decline. 
> Overall, over 80% of reasons were attributable to reversible or treatable 
> causes. 
> Most people who experienced a sudden worsening of symptoms recovered fully, 
> but a third of people experienced recurrent episodes. One in six people 
> suffered permanent decline. Those people most prone to sudden or transient 
> worsening were those who had Parkinson's Disease for nearly eight years or 
> more, had more severe symptoms, had greater use of dopaminergic drugs, and had 
> a greater prevalence of motor complications.
> 
> www.viartis.net
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