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Hi Linda. As I said last week or the week before, Laureen has used Requip for the past four or so years, successfully. She didn't taper off Sinemet. Well, I guess she did, unofficially, because the dyskinesia SInement eventually caused were as bad as the PD tremors. So, she tried taking less of the medication. No happy medium, so she opted for DBS. Best PD-related move she ever made. The DBS controls her tremors and eliminates dyskinesia. Requip helps her mobility. Good luck. Scott Scott E. Antes Northern Arizona University Department of Anthropology PO Box 15200 Flagstaff, AZ 86011 ________________________________________ From: Parkinson's Information Exchange Network [[log in to unmask]] on behalf of Linda [[log in to unmask]] Sent: Monday, August 27, 2012 8:59 AM To: [log in to unmask] Subject: Requip I am currently in the process of being switched from Sinemet to Requip. Has anyone done this? I'm really hoping it will work well as Sinemet is only effective for so long. The doc is titrating me up on requip, then going to titrate me down on Sinemet. She said that Sinemet was very dangerous to stop without slow titrating down. Seems like I should have been told that when I first was prescribed it. I started on Sinemet in May of 2010 so have been taking it for about 2 years and 3 months. Linda ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn