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Ldopa is still the´gold standard´. It has side effects but its efficacy goes on for many years. All agonists have side effects also and are usually not prescribed for people aver 65 years old, at least in Europe because of the possible cognitive effects. Every PWP is different and everyone can choose the best treatment/ maryse ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn