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http://www.ncbi.nlm.nih.gov/pubmed/10495047

Mov Disord. <http://www.ncbi.nlm.nih.gov/pubmed/10495047#> 1999
Sep;14(5):836-8.
Punding on L-dopa.
Fernandez HH<http://www.ncbi.nlm.nih.gov/pubmed?term=Fernandez%20HH%5BAuthor%5D&cauthor=true&cauthor_uid=10495047>,
Friedman JH<http://www.ncbi.nlm.nih.gov/pubmed?term=Friedman%20JH%5BAuthor%5D&cauthor=true&cauthor_uid=10495047>
.
Source

Department of Neurology, Brown University School of Medicine, Memorial
Hospital of Rhode Island, Pawtucket 02860, USA.
Abstract

"Punding" is a stereotypical motor behavior in which there is an intense
fascination with repetitive handling and examining of mechanical objects,
such as picking at oneself or taking apart watches and radios or sorting
and arranging of common objects, such as lining up pebbles, rocks, or other
small objects. It is thought to be dopamine-related although only a single
report of punding in a patient with Parkinson's disease (PD) resulting from
L-dopa has been reported. We describe three additional cases. All were
women aged 65-72 years with a PD duration between 10 and 20 years, on
500-1900 mg L-dopa per day. One spent hours in the market fascinated by
cans. At home she endlessly examined and catalogued her jewelry. Another
picked threads in rugs indoors and weeded her garden compulsively to the
point of wetting herself rather than stopping. The third hoarded
flashlights taking them apart and reassembling them. All improved with
reduction of their anti-PD medications. We think punding is an uncommon but
overlooked complication of dopaminergic drugs.
PMID:10495047 [PubMed - indexed for MEDLINE]
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