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It's a new one for me..;-))

Nic 61/19


On 31 May 2013 16:32, Kathleen Cochran <[log in to unmask]> wrote:

> http://www.ncbi.nlm.nih.gov/pubmed/10495047
>
> Mov Disord. <http://www.ncbi.nlm.nih.gov/pubmed/10495047#> 1999
> Sep;14(5):836-8.
> Punding on L-dopa.
> Fernandez HH<
> http://www.ncbi.nlm.nih.gov/pubmed?term=Fernandez%20HH%5BAuthor%5D&cauthor=true&cauthor_uid=10495047
> >,
> Friedman JH<
> http://www.ncbi.nlm.nih.gov/pubmed?term=Friedman%20JH%5BAuthor%5D&cauthor=true&cauthor_uid=10495047
> >
> .
> Source
>
> Department of Neurology, Brown University School of Medicine, Memorial
> Hospital of Rhode Island, Pawtucket 02860, USA.
> Abstract
>
> "Punding" is a stereotypical motor behavior in which there is an intense
> fascination with repetitive handling and examining of mechanical objects,
> such as picking at oneself or taking apart watches and radios or sorting
> and arranging of common objects, such as lining up pebbles, rocks, or other
> small objects. It is thought to be dopamine-related although only a single
> report of punding in a patient with Parkinson's disease (PD) resulting from
> L-dopa has been reported. We describe three additional cases. All were
> women aged 65-72 years with a PD duration between 10 and 20 years, on
> 500-1900 mg L-dopa per day. One spent hours in the market fascinated by
> cans. At home she endlessly examined and catalogued her jewelry. Another
> picked threads in rugs indoors and weeded her garden compulsively to the
> point of wetting herself rather than stopping. The third hoarded
> flashlights taking them apart and reassembling them. All improved with
> reduction of their anti-PD medications. We think punding is an uncommon but
> overlooked complication of dopaminergic drugs.
> PMID:10495047 [PubMed - indexed for MEDLINE]
> Publication Types, MeSH Terms,
> Substances<http://www.ncbi.nlm.nih.gov/pubmed/10495047#>
> LinkOut - more resources <http://www.ncbi.nlm.nih.gov/pubmed/10495047#>
>
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