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not for Sinemet, but the first time I took mirapexin (pramipexole) I vomited the tablet three times and eventually kept it down by not opening my mouth. > Date: Sun, 29 Jun 2014 09:26:17 -0430 > From: [log in to unmask] > Subject: Can you verify the validity of this? > To: [log in to unmask] > > Nausea and vomiting can be a problem as Sinemet is being introduced. This is because the dose of carbidopa is not large enough to control these side effects. Ironically, the nausea and vomiting often get better as the levodopa/carbidopa dose is increased. The controlled-release preparation, Sinemet CRTM, is absorbed more slowly and far less likely to cause early side effects. Taking the drug with a light meal or snack can also help these side effects. > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn