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I'm finding Apomorhine injections quite helpful in reducing the severity of my "off" periods, though not quite as good as I'd hoped. I inject 5mg in the morning and often again late afternoon. Off periods still there but less severe - no spending chunks of the afternoon lying angrily on the floor waiting for the next sinemet to hit home. Now I can lurch about. Jabbing self in the belly with shaky hands a bit ouchy but bearable - quick stab better than slow push. Amanda ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn