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Guess I wasn't very clear. Of course we know the concept and expectation of on/off, but I don't know what those symptoms are in others. Some talk of freezing, others shaking and tremors, some with nausea, etc. Sue has almost none of those at off times (maybe a few small tremors) but just feels overall 'bad'. And drowsy. J -----Original Message----- >From: mschild <[log in to unmask]> >Sent: Jan 2, 2016 9:28 AM >To: John <[log in to unmask]>, [log in to unmask] >Subject: Re: L-dopa debate > >> Who really knows? >how long has she been on dopa? ( or agonist?). since on/off is a side >effect of treatment.... >maryse ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn