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SOCAAR is pleased to announce our next seminar:
Tuesday, March 22, 2016
4 – 5 PM
200 College Street, WB 215
The influence of clothing on exposure to methamphetamine, phthalates and nicotine
Glenn Morrison
Professor
Civil, Architectural and Environmental Engineering
Missouri University of Science & Technology
Analyses of exposure to indoor air pollutants focus primarily on inhalation of gases and particles. However, other routes of exposure can become important for lower volatility chemicals. In this seminar, clothing
is investigated as a vehicle for concentrating lower volatility organic species such as methamphetamine, phthalates and nicotine, which can then be taken up by oral or dermal routes. Methamphetamine is an example of a highly water (and saliva) soluble compound
that can become highly concentrated in clothing simply by air-to-fabric transfer. Toddlers that mouth fabrics in a house with even very-low concentrations of methamphetamine can ingest a substantial dose. We also hypothesized that wearing clothing should increase
dermal uptake if the fabric was first allowed to equilibrate with certain SVOCs present in indoor air. Simple mass transport models demonstrate that close-fitting clothing would reduce external mass-transport resistance and increase uptake relative to bare
skin. To experimentally assess the effect, we measured uptake of selected airborne phthalates for an individual wearing clean clothes or air-exposed clothes and compared these results with dermal uptake for bare-skinned individuals under otherwise identical
experimental conditions. When compared against the average results for bare-skinned participants, clean clothes were protective, whereas clothes exposed to phthalates dramatically increased dermal uptake of DEP and DnBP. Preliminary experiments with nicotine
also show that clothing is also likely to contribute to dermal dose in environments subject to tobacco smoke or vaping.
If you are unable to join us for the seminar in person, we will be broadcasting the presentations live during the seminar using GoToMeeting software. Please feel free to join us online using
a web-browser or by calling in and using the webviewing software. If you do decide to join us, please remember to mute your microphone. If you have any questions during the meeting you are welcome to contact me by email, or by using the GoToMeeting chat.
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