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I hear you, Ray... On Saturday, April 23, 2016, Rayilyn Brown <[log in to unmask]> wrote: > I'm just desperate for a cure after 20 years with PD. There is lots of > research going on, you'd think something would help. At age 80 there's > not much hope. > > -----Original Message----- From: Trauti Boyd > Sent: Friday, April 22, 2016 4:16 AM > To: [log in to unmask] > Subject: Re: blood test for PD invented > > but accoerding to the other link you posted, ray - why is a cure taking > that > long - biomarkers would come in very handy :) > ' > There is no biomarker. > > A biomarker is any indicator that can be measured objectively in an > individual with a specific disease. It changes with disease progression and > treatment. An example of a biomarker would be your cholesterol level > measured in blood work No such marker exists in Parkinson's. and this > hinders research. Being able to determine which potential therapies are > promising and worth pursuing because scientists can see their effect on a > measurable biomarker in the lab would be invaluable. > > For example research into treatments for diabetes can look at blood glucose > levels as one of their markers because they know that lower blood sugar > levels are good for patients. If a treatment under development helps lower > blood glucose, then it is worth pursuing. Having some sort of indicator for > PD would allow researchers to focus on those avenues that promise the best > results. > > ----- Original Message ----- From: "Rayilyn Brown" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Friday, April 22, 2016 2:14 AM > Subject: Re: blood test for PD invented > > > I agree, Kathleen >> >> -----Original Message----- From: Kathleen Cochran >> Sent: Thursday, April 21, 2016 6:03 AM >> To: [log in to unmask] >> Subject: Re: blood test for PD invented >> >> In every article I've ever seen about biomarkers, there's text like this >> (from the article Ray posted): >> >> "So if you knew earlier that this was happening you might be able to do >> something about it, particularly in the future when maybe better >> treatments >> might become available." >> >> Seems to me the helpfulness of biomarkers is pretty seriously limited by >> the absence of treatments that will slow or reverse disease progression. >> Under present conditions, biomarkers might be seen as stealing a few years >> of blissful ignorance, when you don't yet know you have this disease. >> >> Or insurance companies might find a better way to deny coverage, or >> potential employers might choose not to hire someone known to be headed >> for >> PD. >> >> If someone can make a case for the value to patients of biomarkers without >> better treatment, I would love to hear it. >> >> Kathleen >> >> >> >> >> >> On 20 April 2016 at 22:00, Rayilyn Brown <[log in to unmask]> wrote: >> >> http://www.abc.net.au/am/content/2016/s4446582.htm >>> >>> Ray >>> Rayilyn Brown >>> Past Director AZNPF >>> Arizona Chapter National Parkinson Foundation >>> >>> ---------------------------------------------------------------------- >>> To sign-off Parkinsn send a message to: mailto: >>> [log in to unmask] >>> In the body of the message put: signoff parkinsn >>> >>> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: mailto: >> [log in to unmask] >> In the body of the message put: signoff parkinsn >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: mailto: >> [log in to unmask] >> In the body of the message put: signoff parkinsn >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto: > [log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto: > [log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn