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Subject: 	Parkinson's News Today Daily Digest
Date: 	Fri, 13 Mar 2020 19:01:20 +0000
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Parkinson's News Today Daily Digest
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  Parkinson's News Today Daily Digest

*Contents:*

  * Going Numb Means Going Nowhere in Trying Times <#mctoc1>
  * Discovery of ‘Master Controller’ Region of Alpha-Synuclein
    Aggregation Opens Door to New Therapies <#mctoc2>
  * New Brain Pathway Key to Movement Found in PD Patients, Study
    Reports <#mctoc3>
  * Vermont Couple Shares Strategies on Managing Neurodegenerative
    Disease <#mctoc4>
  * Study Finds Higher Inflammatory Markers in GBA-associated
    Parkinson’s <#mctoc5>
  * How Your Smartphone Can Help You Manage Parkinson’s <#mctoc6>
  * My Parkinson’s Journey Is Like a Seed Waiting to Sprout <#mctoc7>
  * Neurosteer Promotes Wearable Monitor to Detect Early Parkinson’s
    <#mctoc8>
  * MJFF Supports Lundbeck Research in Diagnosing Parkinson’s <#mctoc9>
  * Different Patient, Different Treatment: Precision Medicine Advances
    for Parkinson’s Disease <#mctoc10>


    Going Numb Means Going Nowhere in Trying Times


      Mar 13, 2020 09:00 am | Dr. C


numbSobbing, she throws her arms around me. “I just can’t take one more 
thing. I’m totally overwhelmed. All the things I need to attend to are 
flying around me, and as I try to grasp onto one, I come away empty.” 
She rests in my embrace and the storm slowly subsides. Lying with her is […]

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    Discovery of ‘Master Controller’ Region of Alpha-Synuclein
    Aggregation Opens Door to New Therapies


      Mar 13, 2020 08:00 am | Forest Ray, PhD


Alpha-Synuclein AggregationScientists have discovered a “master 
controller” region that regulates aggregation of 
the alpha-synuclein protein, one of the distinctive features of 
Parkinson’s disease that is known to lead to the progressive 
degeneration of brain cells. Understanding how the master controller 
works opens new opportunities in both the design of new therapies and in 
understanding the disease itself. The […]

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    New Brain Pathway Key to Movement Found in PD Patients, Study Reports


      Mar 13, 2020 07:00 am | Steve Bryson PhD


new brain pathwayPlacing electrodes directly in the brains of people 
with Parkinson’s disease revealed a “hyperdirect” pathway between two 
regions of the brain responsible for movement and cognition, a study 
reported. This pathway was shown to be important in being able to stop 
body movements once initiated. Modulating or controlling this pathway 
may be a therapeutic strategy […]

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    Vermont Couple Shares Strategies on Managing Neurodegenerative Disease


      Mar 12, 2020 09:30 am | Helen Simon


supportLike many couples, Joe and Linda Lacroix of Milton, Vermont, 
spent much of their lives working, raising families, maintaining their 
home, and planning for the future. Unlike most, however, there was 
always a dark cloud looming on their horizon — a gene for Huntington’s 
disease carried by Joe’s mother. After Joe, 67, was diagnosed in […]

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    Study Finds Higher Inflammatory Markers in GBA-associated Parkinson’s


      Mar 12, 2020 07:00 am | Marisa Wexler


GBA mutations, Parkinson'sPeople with Parkinson’s disease associated 
with mutations in the GBA gene have elevated levels of inflammatory 
signaling molecules in their blood, a new study suggests. The study, 
“Plasma Cytokines Profile in Patients with Parkinson’s Disease 
Associated with Mutations in GBA Gene,” was published in the Bulletin of 
Experimental Biology and Medicine. Some mutations in the gene […]

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    How Your Smartphone Can Help You Manage Parkinson’s


      Mar 11, 2020 03:00 pm | Mary Beth Skylis


CBDMy dad was a firm believer in his flip phone and knew it would 
survive if he dropped it from a considerable height. He counted on it to 
connect him with his real estate clients and get the job done. After his 
diagnosis of Parkinson’s disease, my siblings and I realized that voice 
tools might […]

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    My Parkinson’s Journey Is Like a Seed Waiting to Sprout


      Mar 11, 2020 09:00 am | Sherri Woodbridge


kitSometimes we say “I’m sorry” and we mean it. Sometimes we say “Thank 
you” and we mean it. And sometimes, we don’t mean it at all. Let me 
explain When we are overwhelmed with living, stress takes over and we 
are weary and worn out. It feels as if we have nothing left to give. […]

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    Neurosteer Promotes Wearable Monitor to Detect Early Parkinson’s


      Mar 11, 2020 07:00 am | Larry Luxner


NeurosteerWithin a few years, doctors will be able to remotely evaluate 
patients for their risk of developing Alzheimer’s disease, Parkinson’s 
disease and frontotemporal dementia — without having to hook them up to 
expensive, cumbersome machines generally found only in hospitals. That’s 
the vision of Israeli entrepreneur Nathan Intrator, CEO of Neurosteer. 
“Millions of people suffer […]

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    MJFF Supports Lundbeck Research in Diagnosing Parkinson’s


      Mar 11, 2020 07:00 am | Mary Chapman


Lundbeck grantThe Michael J. Fox Foundation for Parkinson’s Research 
(MJFF) is supporting efforts by pharmaceutical company Lundbeck to find 
a new way to diagnose Parkinson’s Disease patients earlier and more 
effectively. With a $1.3 million DKK (Danish krone) grant ($197,000 
U.S.), Lundbeck plans to develop and validate a diagnostic test that 
uses the cerebrospinal fluid that flows […]

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    Different Patient, Different Treatment: Precision Medicine Advances
    for Parkinson’s Disease


      Mar 10, 2020 07:00 am | Forest Ray, PhD


Lundbeck grantThe discovery that abnormal cellular mechanisms are 
specific to distinct groups of sporadic Parkinson’s patients brings 
precision medicine for this neurodegenerative disorder one step closer 
to reality. A recent study suggests that identifying these individual 
disease differences and assessing neuroprotective treatments specific to 
each one is a promising approach to personalized treatments. The study, 
“Deep […]

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