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ORGANIZER;CN=Natalie Leung:mailto:[log in to unmask]
ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=TRUE;CN=LISTSERV.s
ocaar-l:mailto:[log in to unmask]
ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=TRUE;CN="Thomson, E
rrol (HC/SC)":mailto:[log in to unmask]
ATTACH:CID:[log in to unmask]
DESCRIPTION;LANGUAGE=en-US:Hi Everyone\,\n\nHappy New Year!\n\n\nSOCAAR is
pleased to announce our first SOCAAR Seminar for 2024:\n\n\n\nPlease join
us Online on:\n\n\n\nWednesday\, Jan 17\, 2024 3:00PM - 4:00PM EST\n\n3:00
PM - 4:00PM EST\nDr. Errol Thomson\n\nResearch Scientist\n\nInhalation Tox
icology Laboratory\, Health Canada\n\nDepartment of Biochemistry\, Microbi
ology & Immunology\, University of Ottawa\n\n\n\n\n\n\n\n\n\nFrom biologic
al plausibility to predictive models: air pollution\, stress\, and determi
nants of toxicity\n\nAbstract:\nWhen epidemiological studies first showed
compelling evidence of associations between ambient levels of fine airborn
e particles and increased cardiopulmonary mortality\, toxicologists were c
hallenged to assess their biological plausibility. It is now generally acc
epted that air pollution is one of the top risk factors for mortality worl
dwide. However\, associations between exposure to air pollutants and an ev
er-increasing range of adverse health outcomes – including dementia\, de
pression\, obesity\, diabetes\; all conditions with a substantial and grow
ing population prevalence - continue to raise mechanistic questions. Moreo
ver\, the spatial and temporal variability of air pollution poses challeng
es in identifying key determinants of toxicity that would allow us to move
beyond mass-based standards.\nThis seminar will describe work establishin
g how the body’s stress response system – essential for survival but d
eleterious when chronically activated – acts as a key mechanism underlyi
ng systemic effects of air pollution on health. It will then describe how
toxicological tools are being applied to link biological effects to pollut
ant composition\, and hence source. Finally\, it will provide examples of
how use of more human-relevant toxicological tools\, and translation of to
xicological findings to the population\, may help us to better understand
factors underlying susceptibility and identify toxicity determinants.\n\n\
n_________________________________________________________________________
_______\nMicrosoft Teams meeting\nJoin on your computer\, mobile app or ro
om device\nClick here to join the meeting\nMeeting
ID: 233 093 576 326\nPasscode: bx4p6H\nDownload Teams | Join on the web\nOr call in (audio only)\n+1 6
47-794-1609\,\,67023358# Canada\, Toronto
\nPhone Conference ID: 670 233 58#\nFind a local number | Reset
PIN\nLearn More<
https://aka.ms/JoinTeamsMeeting> | Meeting options[log in to unmask]&messageId=0&language=en-US>
\n________________________________________________________________________
________\n\n
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010000000EBAF900390B84C46A65875348031A6D1
SUMMARY;LANGUAGE=en-US:SOCAAR Seminar - Dr. Errol Thomson
DTSTART;TZID=Eastern Standard Time:20240117T150000
DTEND;TZID=Eastern Standard Time:20240117T160000
CLASS:PUBLIC
PRIORITY:5
DTSTAMP:20240110T210717Z
TRANSP:OPAQUE
STATUS:CONFIRMED
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