Bob Newbrough - This message is particularily for you Bob, but I also posted it as it may contain some points of interest for others: Re Exersize - I have just read several notes here on the Prodigy BB concerning 'Exersize'. Of those I felt that the message by Will Johnston reflected my condition the closest....I am now 72 yrs old. Before I was DX'd with PD in 1985 I was quite active both mentally and physically. I started each day with a 30 minute workout combining Aerobic and Calesthenic (sp?) exersizes. However, co-incidental with the beginnings of PD I noticed a decreasing muscle tone despite the exersizing. Also the exertion left me tired to a point where I felt I needed to rest. In an effort to balance exersize and exertion I cut back on the exersizing. This cut-back became greater as time went on. Part of my reasoning was that if I was tiring to a point where I had no energy left to pursue other daily activities then my existance was merely to exersize and while that may be a rewarding goal for some I preferred to use what energy I had in other ways. AT any rate I still am able to live a fairly full lifestyle (albeit s-l-o-w) by keeping my physical exertion to a minimum. My health and heart remain strong and the advance of PD seems minimal. I take 5 gms Eldepryl twice daily in the hopes of extending my functioning lifestyle and Sinamet 25/100 also twice daily. In regsrds to the Sinamet - I have experimented with varying dosages and found that more (4 X daily) had little or no effect but I did notice a slight negative effect when I dropped the doseage to 0. My understanding of these two medications is - Sinamet supposedly gives short-term systematic relief and Eldepryl long term slowdown of PD progression. Therefore an absence of Sinamet is merely uncovering symptoms but a lack of Eldepryl might well increase the progression of those symptoms. Does any of this make sense?....ED H ([log in to unmask])