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Barbara...During one of my many attempts to reduce all medications, I was working at eliminating bromocriptine, but found that on less than 4 x 2.5 mg per day, I developed gait problems, in particular my left foot would turn in until I was almost tripping over it. As soon as I returned to the 4 x 2.5 mg dose, the twisting stopped. Are you taking bromocriptine? I have a question about Sinemet. What happens to the carbidopa part of Sinement? I know it is needed to get the L-dopa into the brain blood system. What happens to it after that? There is so much of the carbidopa in Sinemet CR, I have a feeling it hangs around in my brain like some kind of sludge! Talk to you again soon. Moira MacPherson ([log in to unmask]) -- Peter J. [log in to unmask]