Has anyone used the muscle relaxant BACLOFEN (Lioresal) for leg spasms or foot cramps? I know it is used for MS as well as spinal cord injuries - but what about PD? I save one of my 3 daily doses of Sinemet CR 25/100 for the inevitable spasms and cramps or Restless Leg Syndrome which comes at bedtime, but I would rather use the Sinemet during the day - for sure I don't want to add a 4th dose at bedtime as I'm trying to keep the daily dosage as low as possible. Your input for or against is appreciated. Barbara Yacos <[log in to unmask]>