I have been using Amantadine for the last ten years with good results. I took three a day at mealtimes. Since my Pallidotomy last Dec. however, I only take one a day. A side benefit of Amantadine is that it protects against the flu. Concerning Parlodel I used to be on that taking 8 pills a day. Then I switched over to Permax taking only 4 pills per day with more effective results. Permax is also cheaper than Parlodel. Since my Pallidotomy I only take 1 1/2 Permax a day. Permax seems to be more effective for younger patients while Parlodel is more effective for older patients. Don Berns