Last week I send a message, but I never received an answer from anybody. Maybe the list was inactive. I'm resending it since my contractures are even more painful than before. I hope someone can comment similar experience. Hy, everybody! I'm an "old" (about 8 months) hand at the list, which has been invaluable in the mamanagement of my PD (diagnosed 15 years ago) I'm 57 years old, male, living in Mexico and now quite worried because a precipitous downturn in my symptoms, rigidity, freezing, but above all, very painful muscle contractions, that nobody knows here how to fight. They are most prominent in the chest, shoulders, back and groin, and seem to be more associated with the OFF periods. I used to have strong dyskinesias, but now they are less strong and frequent, so I assume that this pain is due to a lessening the effect of Sinemet that I take in liquid form 8 tablets of 100/25, combined with 4 Permax, of 1mg. plus Vit. C, in 800 c.c. of distilled water. Then I take 50 cc. each hour from 8 am to 11 pm. Has anyone experienced pain due to rigidity, and what did you do? The only relief from pain used to be Xanax (Alprazolam), but know the relief is shorter and the dose is larger, and I'm aware of the addictive side effect. I've decided to have a pallidotomy next month in Denver with a neurologist that is not only a very capable professional, but a human been, concerned, involved , quite different from the wealth of neurologists and neurosurgeons that we consulted in all this years. And because of that, I'm willing to be his first case. (Besides the fact that other places that my Denver doctor referred me, Emory they not only didn't annswer, but I know that there is a 1 year of waiting list) . Many thanks for any comment and suggestion. Sergio Guzik, Mexico ([log in to unmask])